20210801 20180803 20180228 20210801 IID50123 P2X purinoceptor 4 ATP receptor Purinergic receptor Rattus norvegicus 388 P51577 Receptor for ATP that acts as a ligand-gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin. 0 0 0 0 P2rx4 P2RX4_RAT MAGCCSVLGSFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSVVSSVTTKAKGVAVTNTSQLGFRIWDVADYVIPAQEENSLFIMTNMIVTVNQTQSTCPEIPDKTSICNSDADCTPGSVDTHSSGVATGRCVPFNESVKTCEVAAWCPVENDVGVPTPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTSYLKSCIYNAQTDPFCPIFRLGTIVEDAGHSFQEMAVEGGIMGIQIKWDCNLDRAASLCLPRYSFRRLDTRDLEHNVSPGYNFRFAKYYRDLAGKEQRTLTKAYGIRFDIIVFGKAGKFDIIPTMINVGSGLALLGVATVLCDVIVLYCMKKKYYYRDKKYKYVEDYEQGLSGEMNQ 1 2bp5P 375 384 order 1 2 2rupA 111 167 order 2 1 2bp5 X-RAY 7.1 15985462 S.J.ROYLE,O.S.QURESHI,L.K.BOBANOVIC,P.R.EVANS,D.J.OWEN,R.D.MURRELL-LAGNADO 2005 J.CELL.SCI 118 3073 x-ray 2bp5 P 375 384 100 0 1 2bp5_1 1875 Hetero dimer 2bp5P P51577 IID50123 2bp5M P84092 IID50122 2bp5P-2bp5M 2 2rup NMR T.IGAWA,Y.ABE,M.TSUDA,K.INOUE,T.UEDA 2015 FEBS LETT. nmr 2rup A 111 167 100 0 1 2rup_1 3026 Monomer monomer 2rupA P51577 IID50123 ProS 1 predicted 1 375 384 The unbound state of this region is deduced to be disordered based on the results of prediction tools (DICHOT, Mobi, d2p2 etc). 6-282,284-284,289-377 1-5,283-283,285-288,378-388 4-379 1-3,380-388 380-388 359-374