STRUCTURE OF CALMODULIN COMPLEXED WITH AN OLFACTORY CNG CHANNEL FRAGMENT AND ROLE OF THE CENTRAL LINKER: RESIDUAL DIPOLAR COUPLINGS TO EVALUATE CALMODULIN BINDING MODES OUTSIDE THE KINASE FAMILY.

20210801 20180803 20180228 20210801 IID50188 Cyclic nucleotide-gated olfactory channel Cyclic nucleotide-gated cation channel 2 Cyclic nucleotide-gated channel alpha-2 Bos taurus 663 Q03041 Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons. Cytoplasm, Cytoskeleton. SL-0090 unkown Cytoplasm. SL-0086 unkown Nucleus. SL-0191 unkown 0 0 0 0 CNGA2 CNGA2_BOVIN MTEKANGVKSSPANNHNHHAPPAIKASGKDDHRASSRPQSAAADDTSSELQQLAEMDAPQQRRGGFRRIARLVGVLREWAYRNFREEEPRPDSFLERFRGPELHTVTTQQGDGKGDKDGEGKGTKKKFELFVLDPAGDWYYRWLFLIALPVLYNWCLLVARACFSDLQKGYYIVWLVLDYVSDVVYIADLFIRLRTGFLEQGLLVKDTKKLRDNYIHTMQFKLDVASIIPTDLIYFAVGIHNPEVRFNRLLHFARMFEFFDRTETRTSYPNIFRISNLILYILIIIHWNACIYYAISKSIGFGVDTWVYPNITDPEYGYLSREYIYCLYWSTLTLTTIGETPPPVKDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKIDAVKHYMQFRKVSKEMEAKVIRWFDYLWTNKKSVDEREVLKNLPAKLRAEIAINVHLSTLKKVRIFQDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGVTQYALLSAGSCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYPDAKRVLEERGREILMKEGLLDENEVAASMEVDVQEKLEQLETNMDTLYTRFARLLAEYTGAQQKLKQRITVLETKMKQNNEDDSLSDGMNSPEPPAEKP 1 1sy9B 60 63 disorder 1 2 1sy9B 64 82 order 1 3 1sy9B 83 85 disorder 1 1 1sy9 NMR 15803393 G.M.CONTESSA,M.ORSALE,S.MELINO,V.TORRE,M.PACI,A.DESIDERI,D.O.CICERO STRUCTURE OF CALMODULIN COMPLEXED WITH AN OLFACTORY CNG CHANNEL FRAGMENT AND ROLE OF THE CENTRAL LINKER: RESIDUAL DIPOLAR COUPLINGS TO EVALUATE CALMODULIN BINDING MODES OUTSIDE THE KINASE FAMILY. 2005 J.BIOMOL.NMR 31 185 nmr 1sy9 B 60 85 100 2 60 63 83 85 1 1sy9 3903 Hetero dimer 1sy9B Q03041 IID50188 1sy9A P0DP33 IID50309 1sy9A-1sy9B 69-70,72-79,131-421,423-453,455-527,530-586,595-643 1-68,71-71,80-130,422-422,454-454,528-529,587-594,644-663 126-646 1-125,647-663 1-10,52-55,65-83,92-100,116-125 12-23,111-127,278-286