20210801 20180803 20180425 20210801 IID50268 Beclin-1 Coiled-coil myosin-like BCL2-interacting protein Mus musculus 448 O88597 Q99J03 Beclin-1-C 35 kDa localized to mitochondria can promote apoptosis; it induces the mitochondrial translocation of BAX and the release of proapoptotic factors. BH3 106 125 N-acetylmethionine 1 1 Phosphoserine 29 29 Phosphoserine; by AMPK 88 88 Phosphoserine; by AMPK 91 91 Phosphoserine; by AMPK 94 94 Phosphothreonine; by DAPK1 117 117 MEGSKASSSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEEANSGEEPFIETRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQRELKELALEEERLIQELEDVEKNRKVVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQVRYAQIQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLKWGLAWVSSQFYNK 1 3bl2C 106 124 order 1 2 3bl2D 106 124 order 1 1 3bl2 X-RAY 298K 7 18248095 B.KU,J.-S.WOO,C.LIANG,K.-H.LEE,H.-S.HONG,X.E,K.-S.KIM,J.U.JUNG,B.-H.OH 2008 PLOS PATHOG. 4 E25 x-ray 3bl2 C 106 124 100 0 x-ray 3bl2 D 106 124 100 0 1 3bl2_1 949 Hetero dimer 3bl2C O88597 IID50268 3bl2A P89884 3bl2C-3bl2A 2 3bl2_2 949 Hetero dimer 3bl2D O88597 IID50268 3bl2B P89884 3bl2D-3bl2B ProS 1 possible 1, 2 106 124 Same region of human homolog (Q14457, 970dentity) is disordered in the free state. 104-126,193-445 1-103,165-192,446-448 127-164 2794 PF04111 262->443 4.1e-80 Apg6 BARA domain hmm pfm 2795 PF17675 133->259 1.1e-34 Apg6 coiled-coil region hmm pfm 2796 PF15285 103->127 1.4e-20 Beclin-1 BH3 domain, Bcl-2-interacting hmm pfm 7736 PF15285 103->127 2e-06 Beclin-1 BH3 domain, Bcl-2-interacting rps pfm 7737 PF17675 133->259 4e-24 Apg6 coiled-coil region rps pfm 7738 PF04111 262->441 9e-54 Apg6 BARA domain rps pfm 9972 1w1wA 149->303 5e-06 rps scp