20210801 20180803 20180328 20210801 IID50278 Signal transducer and activator of transcription 4 Mus musculus 749 P42228 Carries out a dual function: signal transduction and activation of transcription. 0 0 Phosphotyrosine; by JAK 694 694 MSQWNQVQQLEIKFLEQVDQFYDDNFPMEIRHLLAQWIETQDWEVASNNETMATILLQNLLIQLDEQLGRVSKEKNLLLIHNLKRIRKVLQGKFHGNPMHVAVVISNCLREERRILAAANMPIQGPLEKSLQSSSVSERQRNVEHKVSAIKNSVQMTEQDTKYLEDLQDEFDYRYKTIQTMDQGDKNSILVNQEVLTLLQEMLNSLDFKRKEALSKMTQIVNETDLLMNSMLLEELQDWKKRQQIACIGGPLHNGLDQLQNCFTLLAESLFQLRQQLEKLQEQSTKMTYEGDPIPAQRAHLLERATFLIYNLFKNSFVVERQPCMPTHPQRPMVLKTLIQFTVKLRLLIKLPELNYQVKVKASIDKNVSTLSNRRFVLCGTHVKAMSSEESSNGSLSVEFRHLQPKEMKCSTGSKGNEGCHMVTEELHSITFETQICLYGLTINLETSSLPVVMISNVSQLPNAWASIIWYNVSTNDSQNLVFFNNPPSVTLGQLLEVMSWQFSSYVGRGLNSEQLNMLAEKLTVQSNYNDGHLTWAKFCKEHLPGKTFTFWTWLEAILDLIKKHILPLWIDGYIMGFVSKEKERLLLKDKMPGTFLLRFSESHLGGITFTWVDQSENGEVRFHSVEPYNKGRLSALAFADILRDYKVIMAENIPENPLKYLYPDIPKDKAFGKHYSSQPCEVSRPTERGDKGYVPSVFIPISTIRSDSTEPQSPSDLLPMSPSAYAVLRENLSPTTIETAMNSPYSAE 1 1bgfA 2 123 order 1 1 1bgf X-RAY 9461439 U.VINKEMEIER,I.MOAREFI,J.E.DARNELL JR.,J.KURIYAN 1998 SCIENCE 279 1048 x-ray 1bgf A 2 123 100 0 1 1bgf_1 1852 Homo dimer 1bgfA P42228 IID50278 1bgfA-1bgfA 2-123,138-677 1-1,124-137,678-749 2819 PF01017 140->308 6.5e-53 STAT protein, all-alpha domain hmm pfm 2820 PF02865 2->119 1.5e-41 STAT protein, protein interaction domain hmm pfm 2821 PF02864 323->455 7.6e-36 STAT protein, DNA binding domain hmm pfm 2822 PF00017 574->629 3.1e-16 SH2 domain hmm pfm 5165 1bf5A2 317->565 1.1e-100 hmm scp 5166 1bg1A1 136->317 4.5e-59 hmm scp 5167 1bgfA_ 1->121 2.2e-45 hmm scp 5168 1bg1A3 566->702 2.3e-45 hmm scp 7762 PF02865 2->119 3e-29 STAT protein, protein interaction domain rps pfm 7763 PF01017 141->308 3e-25 STAT protein, all-alpha domain rps pfm 7764 PF02864 330->455 3e-23 STAT protein, DNA binding domain rps pfm 9991 1bgfA 1->123 3e-39 rps scp 9992 1bg1A1 136->317 4e-36 rps scp 9993 1bg1A2 318->565 6e-67 rps scp 9994 1bg1A3 566->703 3e-37 rps scp