20210801 20180803 20180228 20210801 IID50284 Nucleolysin TIA-1 RNA-binding protein TIA-1 T-cell-restricted intracellular antigen-1 Mus musculus 386 P52912 Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis (By similarity). 0 0 N-acetylmethionine 1 1 Tia1 TIA1_MOUSE MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVSQSSPNNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQIGYPPTYGQWGQWYGNAQQIGQYVPNGWQVPAYGVYGQPWSQQGFNQTQSSAPWMGPNYSVPPPQGQNGSMLPSQPAGYRVAGYETQ 6 2rneA 87 89 high_rmsd 1 7 2rneA 174 188 high_rmsd 1 8 2dgoA 87 89 high_rmsd 2 9 2dgoA 174 188 high_rmsd 2 9 2dgoA 87 92 order 2 10 2dgoA 104 199 order 2 9 2rneA 87 92 order 1 10 2rneA 104 199 order 1 1 2rne NMR 18500819 K.KUWASAKO,M.TAKAHASHI,N.TOCHIO,C.ABE,K.TSUDA,M.INOUE,T.TERADA,M.SHIROUZU,N.KOBAYASHI,T.KIGAWA,S.TAGUCHI,A.TANAKA,Y.HAYASHIZAKI,P.GUNTERT,Y.MUTO,S.YOKOYAMA 2008 BIOCHEMISTRY 47 6437 nmr 2rne A 87 199 99 0 1 2rne 1698 Monomer monomer 2rneA P52912 IID50284 2 2dgo NMR C.ABE,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,M.SHIROUZU,S.YOKOYAMA TO BE PUBLISHED nmr 2dgo A 87 199 99 0 1 2dgo 1698 Monomer monomer 2dgoA P52912 IID50284 4-40,45-82,105-183,200-286 1-3,41-44,83-104,184-199,287-386 4-83,103-184,207-287,308-316 1-3,88-96,185-206,288-307,317-386 201-206,303-307,317-346,352-356,375-386 59-65,82-104