20210801 20180803 20180328 20210801 IID50288 Inner nuclear membrane protein HEH2 Helix-extension-helix domain-containing protein 2 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 663 Q03281 D6VT82 Nuclear localization signal 124 137 Phosphoserine 123 123 HEH2 HEH2_YEAST MDHRNLDPKTLKVSQLRRVLVENDVAFPANARKPVLVKLFEEKVRQRLQSSPEASKVRTSIQKVVKSGAKNADRKKTLKSKKLESSSSESKTVKDENVETNKRKREQISTDNEAKMQIQEEKSPKKKRKKRSSKANKPPESPPQSKSDGKATSADLTSELETVEELHKKDSSDDKPRVKELPKPELPNLKVSNEFLAQLNKELASAATENYDHSIKSTDLSSIRIETEEPVGPSTGAETRNESEVMENINLEVQPEVKEAKEELTKISETFDNQDEEDTSRLSSKKNIRSPKGRTRHFIANKTKRGIDIMKPFIAHLFIWLWNGAIFLSIICPILFGLWYREQRIQVGYCGHEKPLKSLAISAFPQTERVDSVLQAYRPNCLECPEHGICSSFMNVECEPGYEPKSSILETYGIIPFPKYCAKDESKEKEVDELVWKVNEYLKKKNAQHECGEGENLFESGETETKLYDIFSHSRPSWESQREFNDHWKNVLEILKKKDDIIWLPLDFETNGKREKSKSNNTNYIYRSTSKKWVTLQCHLEGDIQEYITKYGGSLFITLGVLFLIKKIQSTLDNYVQGEQIIEKLVKEAIDKLKDVKKNKGEEPFLTTVQLRATLLSDIPNIKEQNNLWAQTKEKIMKEQSENIELYLLEENGEIMTCWEWKE 1 4pvzC 100 131 order 1 2 4pvzC 132 137 disorder 1 3 4pvzD 100 109 order 1 4 4pvzD 110 122 disorder 1 5 4pvzD 123 131 order 1 6 4pvzD 132 137 disorder 1 1 4pvz X-RAY 298K 6 26051712 R.K.LOKAREDDY,R.A.HAPSARI,M.VAN RHEENEN,R.A.PUMROY,A.BHARDWAJ,A.STEEN,L.M.VEENHOFF,G.CINGOLANI 2015 STRUCTURE 23 1305 x-ray 4pvz C 100 137 100 1 132 137 x-ray 4pvz D 100 137 100 2 110 122 132 137 1 4pvz_1 2933 Hetero dimer 4pvzC Q03281 IID50288 4pvzA Q02821 IID50012 4pvzC-4pvzA 2 4pvz_2 2934 Hetero dimer 4pvzD Q03281 IID50288 4pvzB Q02821 IID50012 4pvzD-4pvzB ProS 1 predicted 1,5 123 131 Nuclear Localization Signal (NLS). The unbound state of this region is predicted to be disordered by DICHOT and MobiDB. 5-47,191-205,313-355,367-506,523-663 1-4,48-190,206-312,356-366,507-522 7-45,318-512,521-554,573-663 1-6,46-317,513-516,555-572 1-6,555-572 75-92,122-139