20210801201808032018032820210801IID50292Steroid receptor RNA activator 1Steroid receptor RNA activator proteinMus musculus232Q80VJ2E9QM44Q8R0S3Q9CWU7Q9D973Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis (By similarity).00Phosphoserine6060Sra1SRA1_MOUSEMMRCPAGGAEVEMAELYVKPGNKERGWNDPPQFSYGLQTQTGGPKRTPLTKRVAAPQDGSPRAPETSGPPPVDHPPPSSKASRPPPMGSCPATGVEPPSSPVIESETLIEDVLRPLEQALEDCHGHTKKQVCDDISRRLALLREQWAGGKLSIPVKKRMALLVQELLHHQWDAADDIHRSLMVDHVTEVSQWMVGVKRLIAEKKSLSSEETKEEKFTVEPENQTIPGFQQPS22yruA102206order132yruA102104high_rmsd112yruNMRN.NAMEKI,K.SAITO,S.KOSHIBA,T.KIGAWA,S.YOKOYAMASOLUTION STRUCTURE OF MOUSE STEROID RECEPTOR RNA ACTIVATOR 1 (SRA1) PROTEINTO BE PUBLISHEDnmr2yruA102206100012yru3991Monomer monomer2yruAQ80VJ2IID5029226-32,75-76,84-84,106-2111-25,33-74,77-83,85-105,212-23293-1911-92,192-2201-22,212-22057-74,190-203