20210801 20180803 20180228 20210801 IID50299 Transcription elongation factor spt5 Chromatin elongation factor spt5 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 990 O13936 Q9US64 The spt4-spt5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity). 0 0 Phosphoserine 36 36 spt5 SPT5_SCHPO MDTNSPKSIDKDANSTEVDAAEQDAASVKINSTRASPNGSDLLNDDSEAAKITTNEKQSSPVDSHNESPNDTTINKGEDGNENEVDNVNNNDKKEDEDNVEENEEEADANEEEEEDEEDDEEDEEDEDESGGGRRKRARHDRRNQFLDIEAEVDEDEEELEDEEDEIGREDGFIEEEVGADYVGDDRRHRELDRQRQELQSVDAERLAEEYREKYGRSQTVVGDTSNVPQRLLLPSVNDPNIWAVRCKIGKEKDIVFTIMRKAMDLQYTSSPLEIISAFQRDSLVGYIYVEARKQSHVLDALNGVLNVYTNNMILVPIKEMPDLLKVQKQVVELLPGAYVRIRRGKYAGDLAQVDNLSENGLTARVRIVPRIDYSDGLKRKNSATRPQARLFNESEAFKSNPSKFSKRGPRLFLFNNEEFEDGFLVKDIRISSLITEGVNPTLDEVSKFNPNNEDLDLSSLALSVKGGHAEFQPGDHVEVYVGEQTGVSGVVENVRGSVITMVSSDGLRLDVPSRGLRKRFRHGDYVKVIAGKYKDDTGMVVRISKDEVTFLSDTLMTELTVFSRDLGEASSAQAVNSAYELHDLVQLDVNTVACIFSVDRDTYKVIDQNGGVRTVLASQITMRHSNRRGVATDRNGAEIRIGDKVKEVGGEGKQGTILHIYRAFVFLHNRDIAENNGVFSARSRNVATIAAKGARISADLTKMNPALSNGPALPPVANLKRTIGRDKAIGATVRIRRGPMKGLLGVIKDTTDANARVELHTGNKMVTIPKENLLYTTKTGELISYTEFIERSRGIRPGSISTADGPNVPNWAQGARTPAVANGSRTPAWNTGSRTPAWNSGSKTPAWNSGSRTPAWNSGNKTPAWNAGSRTPAWNSGNKTPAWNVGNKTPAWNSGAKTPAWNAGNKTPSWNNGTKTPAWNANQTPMVANGTNTSWGQTPAYGGFSETNWDTEDNSKPYTAPTPGAWAAPTPGGWDDEEGDSPKYVPPSP 1 4pz8B 827 828 disorder 1 2 4pz8B 829 832 order 1 3 4pz8B 833 844 disorder 1 1 4pz8 X-RAY 291K 6 24939935 S.K.DOAMEKPOR,A.M.SANCHEZ,B.SCHWER,S.SHUMAN,C.D.LIMA 2014 GENES DEV. 28 1323 x-ray 4pz8 B 827 844 94 2 827 828 833 844 1 4pz8_1 2940 Hetero dimer 4pz8B O13936 IID50299 4pz8A P40997 IID50316 4pz8B-4pz8A 187-213,228-327,334-375,386-450,471-571,578-693,727-794 1-186,214-227,328-333,376-385,451-470,572-577,694-726,795-990 85-130,139-166,231-461,468-693,724-785 1-84,131-138,167-230,694-723,786-990 170-196,202-230,694-700,786-800,807-990 75-129,131-143,148-177,324-335,645-654,960-975