20250201 IID50356 Myoblast determination protein 1 Mus musculus 318 P10085 Q8C6B1 Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation (PubMed:16901893). Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (PubMed:21798092, PubMed:3175662). 0 0 N6-methyllysine; by EHMT2 104 104 Myod1 Myoblast determination protein 1 MELLSPPLRDIDLTGPDGSLCSFETADDFYDDPCFDSPDLRFFEDLDPRLVHMGALLKPEEHAHFPTAVHPGPGAREDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAFYAPGPLPPGRGSEHYSGDSDASSPRSNCSDGMMDYSGPPSGPRRQNGYDTAYYSEAARESRPGKSAAVSSLDCLSSIVERISTDSPAAPALLLADAPPESPPGPPEGASLSDTEQGTQTPSPDAAPQCPAGSNPNAIYQVL 1 1mdyA 102 166 order 1 2 1mdyB 105 166 order 1 3 1mdyC 105 166 order 1 4 1mdyD 105 166 order 1 5 7wz6B 102 115 disorder 2 6 7wz6B 116 165 order 2 7 7wz6B 166 166 disorder 2 1 1mdy X-RAY 8181063 P.C.MA,M.A.ROULD,H.WEINTRAUB,C.O.PABO 1994 CELL(CAMBRIDGE,MASS.) 77 451 x-ray 1mdy A 102 166 98 0 x-ray 1mdy B 105 166 98 0 x-ray 1mdy C 105 166 98 0 x-ray 1mdy D 105 166 98 0 1 1mdy_1 1813 Homo dimer 1mdyA P10085 IID50356 1mdyB P10085 IID50356 1mdyB-1mdyA 2 1mdy_2 1813 Homo dimer 1mdyC P10085 IID50356 1mdyD P10085 IID50356 1mdyC-1mdyD 2 7wz6 X-RAY 290K 5.5) 35810596 J.ZHONG,Z.JIN,L.JIANG,L.ZHANG,Z.HU,Y.ZHANG,Y.LIU,J.MA,Y.HUANG 2022 BIOCHEM.BIOPHYS.RES.COMMUN. 621 88 x-ray 7wz6 B 102 166 100 2 102 115 166 166 1 7wz6 6818 Hetero dimer 7wz6A P15806 7wz6B P10085 IID50356 7wz6A-7wz6B ProS 1 verified 1,2,3,4 102 115 5 102 115 DNA binding 93-99,101-102,104-169,245-260 1-92,100-100,103-103,170-244,261-318 125-168 1-124,169-318 1-61,80-97,107-124,202-259,299-304,311-318 110-121,169-186,261-286