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IID00728
 UniprotQ16828
ProteinDual specificity protein phosphatase 6
GeneDUSP6
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
381
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-154 Monomer :
 Evidence NMR 1hzm A Reference
       Region 1hzm A 1-154 order
Seq 205-347 Monomer :
 Evidence X-RAY 1mkp A Reference
       Region 1mkp A 205-347 order
 
Prediction
NeProc
Disorder 13-16,108-202,353-381
Order 1-12,17-107,203-352
ProS 13-16,113-151,197-202,362-381
AlphaFold
Disorder 1-15,58-71,75-76,78-80,84-85,90-91,103-112,150-205,350-362,367-367,369-370,375-381
Order 16-57,72-74,77-77,81-83,86-89,92-102,113-149,206-349,363-366,368-368,371-374
Pfam Hmmer
PF00581 19-142 1.3e-05
PF00782 206-346 1e-70
SEG 115-123 ,151-187
Function
Function in SwissProt
Inactivates MAP kinases. Has a specificity for the ERK family.