Search Keyword:


Search option:


IID90023
 UniprotQ70627
ProteinProtein Nef
Genenef
OrganismHuman immunodeficiency virus type 1 group M subtype B
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
206
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 56-158,174-205 Monomer :
 Evidence NMR 2nef A Reference
       Region 2nef A 56-158 order
       Region 2nef A 56-70 high_rmsd
       Region 2nef A 174-205 order
       Region 2nef A 189-190 high_rmsd
Seqphosphorylation
    6-6 Phosphoserine; by host
 
Prediction
NeProc
Disorder 1-30
Order 31-206
ProS 1-30
AlphaFold
Disorder 1-12,21-21,64-66,158-162,205-206
Order 13-20,22-63,67-157,163-204
Pfam Hmmer
PF00469 2-205 6.3e-144
SEG 44-53
Function
Function in SwissProt
Extracellular Nef protein targets CD4(+) T-lymphocytes for apoptosis by interacting with CXCR4 surface receptors.