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IID00917
 UniprotO75143
ProteinAutophagy-related protein 13
GeneATG13
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
517
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-190 Hetero hexadecamer : Q9BSB4
 Evidence X-RAY 5xv4 A Reference
       Region 5xv4 A 1-6 disorder
       Region 5xv4 A 7-144 order
       Region 5xv4 A 145-146 disorder
       Region 5xv4 A 147-190 order
 Evidence X-RAY 5xv4 C Reference
       Region 5xv4 C 1-5 disorder
       Region 5xv4 C 6-144 order
       Region 5xv4 C 145-146 disorder
       Region 5xv4 C 147-190 order
 Evidence X-RAY 5xv4 E Reference
       Region 5xv4 E 1-6 disorder
       Region 5xv4 E 7-144 order
       Region 5xv4 E 145-146 disorder
       Region 5xv4 E 147-190 order
 Evidence X-RAY 5xv4 G Reference
       Region 5xv4 G 1-6 disorder
       Region 5xv4 G 7-144 order
       Region 5xv4 G 145-146 disorder
       Region 5xv4 G 147-190 order
 Evidence X-RAY 5xv4 I Reference
       Region 5xv4 I 1-6 disorder
       Region 5xv4 I 7-144 order
       Region 5xv4 I 145-146 disorder
       Region 5xv4 I 147-190 order
 Evidence X-RAY 5xv4 K Reference
       Region 5xv4 K 1-6 disorder
       Region 5xv4 K 7-144 order
       Region 5xv4 K 145-146 disorder
       Region 5xv4 K 147-190 order
 Evidence X-RAY 5xv4 M Reference
       Region 5xv4 M 1-5 disorder
       Region 5xv4 M 6-144 order
       Region 5xv4 M 145-146 disorder
       Region 5xv4 M 147-190 order
 Evidence X-RAY 5xv4 O Reference
       Region 5xv4 O 1-6 disorder
       Region 5xv4 O 7-144 order
       Region 5xv4 O 145-146 disorder
       Region 5xv4 O 147-190 order
Seq 1-190 Hetero tetramer : Q9BSB4
 Evidence X-RAY 5xuy A Reference
       Region 5xuy A 1-5 disorder
       Region 5xuy A 6-91 order
       Region 5xuy A 92-92 disorder
       Region 5xuy A 93-111 order
       Region 5xuy A 112-113 disorder
       Region 5xuy A 114-144 order
       Region 5xuy A 145-146 disorder
       Region 5xuy A 147-190 order
 Evidence X-RAY 5xuy C Reference
       Region 5xuy C 1-5 disorder
       Region 5xuy C 6-144 order
       Region 5xuy C 145-145 disorder
       Region 5xuy C 146-190 order
 Evidence X-RAY 5xv1 A Reference
       Region 5xv1 A 1-5 disorder
       Region 5xv1 A 6-111 order
       Region 5xv1 A 112-113 disorder
       Region 5xv1 A 114-144 order
       Region 5xv1 A 145-146 disorder
       Region 5xv1 A 147-190 order
 Evidence X-RAY 5xv1 C Reference
       Region 5xv1 C 1-5 disorder
       Region 5xv1 C 6-190 order
 Evidence X-RAY 5xv3 A Reference
       Region 5xv3 A 1-5 disorder
       Region 5xv3 A 6-144 order
       Region 5xv3 A 145-146 disorder
       Region 5xv3 A 147-190 order
 Evidence X-RAY 5xv3 C Reference
       Region 5xv3 C 1-5 disorder
       Region 5xv3 C 6-144 order
       Region 5xv3 C 145-146 disorder
       Region 5xv3 C 147-190 order
Seq 1-197 Hetero hexamer : Q9BSB4
 Evidence X-RAY 8do8 B Reference
       Region 8do8 B 1-4 disorder
       Region 8do8 B 5-196 order
       Region 8do8 B 197-197 disorder
 Evidence X-RAY 8do8 D Reference
       Region 8do8 D 1-4 disorder
       Region 8do8 D 5-194 order
       Region 8do8 D 195-197 disorder
Seq 1-200 Hetero dimer : Q9BSB4
 Evidence X-RAY 5c50 B Reference
       Region 5c50 B 12-195 order
       Region 5c50 B 196-200 disorder
 Evidence X-RAY 5xv6 A Reference
       Region 5xv6 A 1-3 disorder
       Region 5xv6 A 4-144 order
       Region 5xv6 A 145-146 disorder
       Region 5xv6 A 147-190 order
Seq 436-447 Hetero dimer : IID00346Complex
 Evidence X-RAY 3wao A Reference
       Region 3wao A 436-441 disorder
       Region 3wao A 442-447 order
Seq 436-447 Hetero dimer : IID00346Complex
 Evidence X-RAY 3wao B Reference
       Region 3wao B 436-441 disorder
       Region 3wao B 442-447 order
Seq 436-447 Hetero tetramer : IID01019Complex
 Evidence X-RAY 3wan A Reference
       Region 3wan A 436-441 disorder
       Region 3wan A 442-447 order
 Evidence X-RAY 3wan B Reference
       Region 3wan B 436-441 disorder
       Region 3wan B 442-447 order
Seq 436-447 Hetero dimer : IID00346Complex
 Evidence X-RAY 3wao C Reference
       Region 3wao C 436-441 disorder
       Region 3wao C 442-447 order
Seq 436-447 Hetero dimer : IID01013Complex
 Evidence X-RAY 3wap A Reference
       Region 3wap A 436-443 disorder
       Region 3wap A 444-447 order
Seq 436-447 Hetero dimer : IID00346Complex
 Evidence X-RAY 3wao D Reference
       Region 3wao D 436-442 disorder
       Region 3wao D 443-447 order
Seq 441-454 Hetero dimer : IID00921Complex
 Evidence X-RAY 6hyn A Reference
       Region 6hyn A 441-441 disorder
       Region 6hyn A 442-454 order
SeqProS predicted 442-447 This region is predicted to be disordered by NeProc and AlphaFold (pLDDT < 68.5). Hetero dimer : IID00346Complex
       Region 3wao A 442-447 order
SeqProS predicted 442-447 This region is predicted to be disordered by NeProc and AlphaFold (pLDDT < 68.5). Hetero dimer : IID00346Complex
       Region 3wao C 442-447 order
SeqProS predicted 442-447 This region is predicted to be disordered by NeProc and AlphaFold (pLDDT < 68.5). Hetero dimer : IID00346Complex
       Region 3wao B 442-447 order
SeqProS predicted 442-447 This region is predicted to be disordered by NeProc and AlphaFold (pLDDT < 68.5). Hetero dimer : IID00346Complex
       Region 3wao D 443-447 order
SeqProS predicted 442-447 This region is predicted to be disordered by NeProc and AlphaFold (pLDDT < 68.5). Hetero tetramer : IID01019Complex
       Region 3wan A 442-447 order
       Region 3wan B 442-447 order
SeqProS predicted 442-454 This region is predicted to be disordered by NeProc and AlphaFold (pLDDT < 68.5). Hetero dimer : IID00921Complex
       Region 6hyn A 442-454 order
SeqProS predicted 444-447 This region is predicted to be disordered by NeProc and AlphaFold (pLDDT < 68.5). Hetero dimer : IID01013Complex
       Region 3wap A 444-447 order
Seqphosphorylation
    355-355 Phosphoserine; by ULK1
    356-356 Phosphoserine
    361-361 Phosphoserine
Seqacetylation
    1-1 N-acetylmethionine
 
Prediction
NeProc
Disorder 1-6,205-457,463-496,501-517
Order 7-39,47-109,114-199,458-462,497-500
ProS 212-219,226-259,289-300,388-392,439-457,463-483,488-496,501-517
AlphaFold
Disorder 1-4,195-463,473-491,517-517
Order 5-194,464-472,492-516
SEG 121-129 ,170-182 ,253-270 ,425-438
Function
Function in SwissProt
Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.