Search Keyword:


Search option:


IID01006
 UniprotQ96F86
ProteinEnhancer of mRNA-decapping protein 3
GeneEDC3
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
508
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-82 Monomer :
 Evidence X-RAY 2vc8 A Reference
       Region 2vc8 A 1-2 disorder
       Region 2vc8 A 3-74 order
       Region 2vc8 A 75-82 disorder
Seqdisorder 72-101
 Evidence X-RAY Reference
       Region 72-101 disorder
Seqdisorder 192-228
 Evidence NMR Reference
       Region 192-228 disorder
Seq 192-228 Hetero dimer : IID00712Complex
 Evidence X-RAY 2wax B Reference
       Region 2wax B 192-196 disorder
       Region 2wax B 197-226 order
       Region 2wax B 227-228 disorder
 Evidence X-RAY 2wax D Reference
       Region 2wax D 192-198 disorder
       Region 2wax D 199-226 order
       Region 2wax D 227-228 disorder
 Evidence X-RAY 2way B Reference
       Region 2way B 192-198 disorder
       Region 2way B 199-224 order
       Region 2way B 225-228 disorder
 Evidence X-RAY 2way D Reference
       Region 2way D 192-195 disorder
       Region 2way D 196-225 order
       Region 2way D 226-228 disorder
Seq 192-228 Hetero tetramer : IID00712Complex
 Evidence X-RAY 6s8s B Reference
       Region 6s8s B 192-226 order
       Region 6s8s B 227-228 disorder
 Evidence X-RAY 6s8s D Reference
       Region 6s8s D 192-226 order
       Region 6s8s D 227-228 disorder
Seq 203-508 Homo dimer :
 Evidence X-RAY 3d3j A Reference
       Region 3d3j A 203-257 disorder
       Region 3d3j A 258-264 order
       Region 3d3j A 265-267 disorder
       Region 3d3j A 268-321 order
       Region 3d3j A 322-332 disorder
       Region 3d3j A 333-447 order
       Region 3d3j A 448-452 disorder
       Region 3d3j A 453-507 order
       Region 3d3j A 508-508 disorder
 Evidence X-RAY 3d3k A Reference
       Region 3d3k A 250-257 disorder
       Region 3d3k A 258-264 order
       Region 3d3k A 265-267 disorder
       Region 3d3k A 268-323 order
       Region 3d3k A 324-332 disorder
       Region 3d3k A 333-447 order
       Region 3d3k A 448-452 disorder
       Region 3d3k A 453-507 order
       Region 3d3k A 508-508 disorder
 Evidence X-RAY 3d3k B Reference
       Region 3d3k B 250-257 disorder
       Region 3d3k B 258-264 order
       Region 3d3k B 265-267 disorder
       Region 3d3k B 268-323 order
       Region 3d3k B 324-332 disorder
       Region 3d3k B 333-447 order
       Region 3d3k B 448-452 disorder
       Region 3d3k B 453-507 order
       Region 3d3k B 508-508 disorder
 Evidence X-RAY 3d3k C Reference
       Region 3d3k C 250-257 disorder
       Region 3d3k C 258-264 order
       Region 3d3k C 265-267 disorder
       Region 3d3k C 268-323 order
       Region 3d3k C 324-332 disorder
       Region 3d3k C 333-447 order
       Region 3d3k C 448-452 disorder
       Region 3d3k C 453-507 order
       Region 3d3k C 508-508 disorder
 Evidence X-RAY 3d3k D Reference
       Region 3d3k D 250-257 disorder
       Region 3d3k D 258-264 order
       Region 3d3k D 265-267 disorder
       Region 3d3k D 268-323 order
       Region 3d3k D 324-332 disorder
       Region 3d3k D 333-447 order
       Region 3d3k D 448-452 disorder
       Region 3d3k D 453-507 order
       Region 3d3k D 508-508 disorder
SeqProS verified 197-224 Hetero dimer : IID00712Complex
       Region 2way B 199-224 order
       Region 2way D 196-225 order
       Region 2wax B 197-226 order
       Region 2wax D 199-226 order
       Region 192-228 disorder
SeqProS verified 197-224 Hetero tetramer : IID00712Complex
       Region 6s8s B 192-226 order
       Region 6s8s D 192-226 order
       Region 192-228 disorder
Seqphosphorylation
    161-161 Phosphoserine
    140-140 Phosphoserine
    138-138 Phosphoserine
    131-131 Phosphoserine
 
Prediction
NeProc
Disorder 66-215,223-268
Order 1-65,216-222,269-508
ProS 112-120,138-163,186-215,223-228,238-263
AlphaFold
Disorder 1-3,69-202,226-242,252-257,448-451
Order 4-68,203-225,243-251,258-447,452-508
SEG 154-167
Function
Function in SwissProt
Binds single-stranded RNA. Involved in the process of mRNA degradation and in the positive regulation of mRNA decapping. May play a role in spermiogenesis and oogenesis.