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IID01015
 UniprotQ9C0A0
ProteinContactin-associated protein-like 4
GeneCNTNAP4
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
1308
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1301-1308 Hetero dimer : IID00971Complex
 Evidence X-RAY 4nxq D Reference
       Region 4nxq D 1301-1301 disorder
       Region 4nxq D 1302-1308 order
 Evidence X-RAY 4nxq E Reference
       Region 4nxq E 1301-1302 disorder
       Region 4nxq E 1303-1308 order
 Evidence X-RAY 4nxq F Reference
       Region 4nxq F 1301-1302 disorder
       Region 4nxq F 1303-1308 order
SeqProS predicted 1302-1308 This region is predicted to be disordered by NeProc and AlphaFold (pLDDT < 68.5). Hetero dimer : IID00971Complex
       Region 4nxq D 1302-1308 order
       Region 4nxq E 1303-1308 order
       Region 4nxq F 1303-1308 order
 
Prediction
NeProc
Disorder 1-22,27-31,40-51,1024-1025,1224-1230,1265-1308
Order 23-26,32-39,52-251,257-1023,1030-1223,1231-1264
ProS 5-22,27-31,40-51,1024-1025,1224-1230,1265-1308
AlphaFold
Disorder 1-29,126-130,198-204,247-259,297-306,316-325,386-389,413-416,433-433,435-440,475-488,499-503,905-905,1016-1034,1186-1189,1203-1245,1269-1308
Order 30-125,131-197,205-246,260-296,307-315,326-385,390-412,417-432,434-434,441-474,489-498,504-904,906-1015,1035-1185,1190-1202,1246-1268
Pfam Hmmer
212->341 43-174 398->524
SEG 43-53
Function
Function in SwissProt
Presynaptic protein involved in both dopaminergic synaptic transmission and GABAergic system, thereby participating in the structural maturation of inhibitory interneuron synapses. Involved in the dopaminergic synaptic transmission by attenuating dopamine release through a presynaptic mechanism. Also participates in the GABAergic system (By similarity).