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IID50317
 UniprotP43274
ProteinHistone H1.4
GeneH1-4
OrganismMus musculus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
219
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seqdisorder 16-37
 Evidence CD Reference
       Region 16-37 disorder
Seqphosphorylation
    36-36 Phosphoserine
    187-187 Phosphoserine
    18-18 Phosphothreonine
    2-2 Phosphoserine
    146-146 Phosphothreonine
    36-36 Phosphoserine
    146-146 Phosphothreonine
    18-18 Phosphothreonine
    2-2 Phosphoserine
    187-187 Phosphoserine
Seqacetylation
    26-26 N6-acetyllysine; alternate
    17-17 N6-acetyllysine
    2-2 N-acetylserine
    26-26 N6-acetyllysine; alternate
    17-17 N6-acetyllysine
    2-2 N-acetylserine
 
Prediction
NeProc
Disorder 1-41,98-219
Order 42-97
ProS 38-41,98-108
AlphaFold
Disorder 1-37,110-219
Order 38-109
Pfam Hmmer
PF00538 36-109 7.7e-32
SEG 5-15 ,21-34 ,59-69 ,116-219
Function
Function in SwissProt
Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.