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IID50413
 UniprotO08989
ProteinRas-related protein M-Ras
GeneMras
OrganismMus musculus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
208
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-178 Monomer :
 Evidence X-RAY 1x1r A Reference
       Region 1x1r A 1-9 disorder
       Region 1x1r A 10-178 order
 Evidence X-RAY 1x1s A Reference
       Region 1x1s A 1-10 disorder
       Region 1x1s A 11-68 order
       Region 1x1s A 69-73 disorder
       Region 1x1s A 74-178 order
 Evidence X-RAY 3kkp A Reference
       Region 3kkp A 1-10 disorder
       Region 3kkp A 11-178 order
 Evidence X-RAY 3kkq A Reference
       Region 3kkq A 1-8 disorder
       Region 3kkq A 9-178 order
 Evidence X-RAY 3pir A Reference
       Region 3pir A 1-10 disorder
       Region 3pir A 11-178 order
 Evidence X-RAY 3pit A Reference
       Region 3pit A 1-10 disorder
       Region 3pit A 11-178 order
Seq 1-178 Homo trimer :
 Evidence X-RAY 3kko A Reference
       Region 3kko A 1-9 disorder
       Region 3kko A 10-178 order
 Evidence X-RAY 3kko B Reference
       Region 3kko B 1-9 disorder
       Region 3kko B 10-178 order
 Evidence X-RAY 3kko P Reference
       Region 3kko P 1-10 disorder
       Region 3kko P 11-178 order
SeqProS possible 40-48 Same region of the homolog (P01112) is disordered in the free state (PMID: 11320243). Homo trimer :
       Region 3kko A 10-178 order
       Region 3kko B 10-178 order
       Region 3kko P 11-178 order
       Region 3kkq A 9-178 order
       Region 3pir A 11-178 order
       Region 1x1r A 10-178 order
       Region 1x1s A 11-68 order
       Region 3pit A 11-178 order
       Region 3kkp A 11-178 order
SeqProS verified 69-73 :
       Region 3kko A 10-178 order
       Region 3kko B 10-178 order
       Region 3kko B 10-178 order 3
       Region 3kko P 11-178 order
       Region 3kkq A 9-178 order
       Region 3pir A 11-178 order
       Region 1x1r A 10-178 order
       Region 3pit A 11-178 order
       Region 3kkp A 11-178 order
       Region 1x1s A 69-73 disorder
 
Prediction
NeProc
Disorder 1-10,179-208
Order 11-178
ProS 200-208
AlphaFold
Disorder 1-9,180-208
Order 10-179
SEG 17-25 ,182-191
Function
Function in SwissProt
Serves as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Activates the MAP kinase pathway (By similarity).