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IID50415
 UniprotO54788
ProteinDNA fragmentation factor subunit beta
GeneDffb
OrganismMus musculus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
344
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-87 Monomer :
 Evidence NMR 1c9f A Reference
       Region 1c9f A 1-87 order
       Region 1c9f A 1-3 high_rmsd
       Region 1c9f A 87-87 high_rmsd
Seq 1-87 Hetero dimer : O54786
 Evidence NMR 1f2r C Reference
       Region 1f2r C 1-87 order
Seq 1-329 Homo dimer :
 Evidence X-RAY 1v0d A Reference
       Region 1v0d A 1-84 disorder
       Region 1v0d A 85-328 order
       Region 1v0d A 329-329 disorder
 
Prediction
NeProc
Disorder 1-7,328-344
Order 8-327
AlphaFold
Disorder 1-5,327-344
Order 6-326
SEG 330-344
Function
Function in SwissProt
Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology.