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IID50424
 UniprotP04050
ProteinDNA-directed RNA polymerase II subunit RPB1
GeneRPO21
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c)
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
1733
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-1732 Hetero dodecamer : P08518,P16370,P20433,P20434,P20435,P20436,P27999,P34087,P38902
 Evidence X-RAY 4a3c A Reference
       Region 4a3c A 1-2 disorder
       Region 4a3c A 3-1080 order
       Region 4a3c A 1081-1091 disorder
       Region 4a3c A 1092-1176 order
       Region 4a3c A 1177-1186 disorder
       Region 4a3c A 1187-1243 order
       Region 4a3c A 1244-1253 disorder
       Region 4a3c A 1254-1455 order
       Region 4a3c A 1456-1732 disorder
 Evidence X-RAY 4a93 A Reference
       Region 4a93 A 1-2 disorder
       Region 4a93 A 3-1080 order
       Region 4a93 A 1081-1091 disorder
       Region 4a93 A 1092-1176 order
       Region 4a93 A 1177-1186 disorder
       Region 4a93 A 1187-1243 order
       Region 4a93 A 1244-1253 disorder
       Region 4a93 A 1254-1455 order
       Region 4a93 A 1456-1732 disorder
Seq 1-1733 Hetero undecamer : P07273,P08518,P16370,P20434,P20435,P20436,P27999,P38902
 Evidence X-RAY 3gtm A Reference
       Region 3gtm A 1-1 disorder
       Region 3gtm A 2-186 order
       Region 3gtm A 187-194 disorder
       Region 3gtm A 195-1176 order
       Region 3gtm A 1177-1186 disorder
       Region 3gtm A 1187-1243 order
       Region 3gtm A 1244-1253 disorder
       Region 3gtm A 1254-1455 order
       Region 3gtm A 1456-1733 disorder
Seq 1-1733 Hetero undecamer : P08518,P16370,P20434,P20435,P20436,P27999,P29055,P38902
 Evidence X-RAY 3k7a A Reference
       Region 3k7a A 1-1 disorder
       Region 3k7a A 2-154 order
       Region 3k7a A 155-160 disorder
       Region 3k7a A 161-1081 order
       Region 3k7a A 1082-1091 disorder
       Region 3k7a A 1092-1176 order
       Region 3k7a A 1177-1186 disorder
       Region 3k7a A 1187-1243 order
       Region 3k7a A 1244-1253 disorder
       Region 3k7a A 1254-1445 order
       Region 3k7a A 1446-1733 disorder
Seq 1-1733 Hetero dodecamer : P08518,P16370,P20434,P20435,P20436,P27999,P34087,P38902
 Evidence X-RAY 1nt9 A Reference
       Region 1nt9 A 1-1 disorder
       Region 1nt9 A 2-154 order
       Region 1nt9 A 155-160 disorder
       Region 1nt9 A 161-186 order
       Region 1nt9 A 187-198 disorder
       Region 1nt9 A 199-249 order
       Region 1nt9 A 250-258 disorder
       Region 1nt9 A 259-311 order
       Region 1nt9 A 312-323 disorder
       Region 1nt9 A 324-1081 order
       Region 1nt9 A 1082-1091 disorder
       Region 1nt9 A 1092-1176 order
       Region 1nt9 A 1177-1186 disorder
       Region 1nt9 A 1187-1243 order
       Region 1nt9 A 1244-1253 disorder
       Region 1nt9 A 1254-1453 order
       Region 1nt9 A 1454-1733 disorder
Seq 1-1733 Hetero dodecamer : P08518,P16370,P20434,P20435,P20436,P27999,P34087,P38902
 Evidence X-RAY 2b63 A Reference
       Region 2b63 A 1-1 disorder
       Region 2b63 A 2-186 order
       Region 2b63 A 187-194 disorder
       Region 2b63 A 195-1081 order
       Region 2b63 A 1082-1091 disorder
       Region 2b63 A 1092-1176 order
       Region 2b63 A 1177-1186 disorder
       Region 2b63 A 1187-1243 order
       Region 2b63 A 1244-1253 disorder
       Region 2b63 A 1254-1455 order
       Region 2b63 A 1456-1733 disorder
Seq 1-1733 Hetero tridecamer : P08518,P16370,P20433,P20434,P20435,P20436,P27999,P29055,P34087,P38902
 Evidence X-RAY 4bbr A Reference
       Region 4bbr A 1-2 disorder
       Region 4bbr A 3-186 order
       Region 4bbr A 187-194 disorder
       Region 4bbr A 195-1081 order
       Region 4bbr A 1082-1092 disorder
       Region 4bbr A 1093-1175 order
       Region 4bbr A 1176-1186 disorder
       Region 4bbr A 1187-1244 order
       Region 4bbr A 1245-1253 disorder
       Region 4bbr A 1254-1455 order
       Region 4bbr A 1456-1733 disorder
 Evidence X-RAY 4bbs A Reference
       Region 4bbs A 1-2 disorder
       Region 4bbs A 3-186 order
       Region 4bbs A 187-194 disorder
       Region 4bbs A 195-1086 order
       Region 4bbs A 1087-1092 disorder
       Region 4bbs A 1093-1175 order
       Region 4bbs A 1176-1186 disorder
       Region 4bbs A 1187-1244 order
       Region 4bbs A 1245-1253 disorder
       Region 4bbs A 1254-1455 order
       Region 4bbs A 1456-1733 disorder
Seq 1-1733 Hetero decamer : P08518,P16370,P20434,P20435,P20436,P27999,P38902
 Evidence X-RAY 1twa A Reference
       Region 1twa A 1-2 disorder
       Region 1twa A 3-248 order
       Region 1twa A 249-260 disorder
       Region 1twa A 261-305 order
       Region 1twa A 306-323 disorder
       Region 1twa A 324-327 order
       Region 1twa A 328-345 disorder
       Region 1twa A 346-1081 order
       Region 1twa A 1082-1091 disorder
       Region 1twa A 1092-1173 order
       Region 1twa A 1174-1176 disorder
       Region 1twa A 1177-1177 order
       Region 1twa A 1178-1186 disorder
       Region 1twa A 1187-1243 order
       Region 1twa A 1244-1253 disorder
       Region 1twa A 1254-1385 order
       Region 1twa A 1386-1401 disorder
       Region 1twa A 1402-1450 order
       Region 1twa A 1451-1733 disorder
 Evidence X-RAY 1twc A Reference
       Region 1twc A 1-2 disorder
       Region 1twc A 3-248 order
       Region 1twc A 249-260 disorder
       Region 1twc A 261-305 order
       Region 1twc A 306-323 disorder
       Region 1twc A 324-329 order
       Region 1twc A 330-345 disorder
       Region 1twc A 346-1081 order
       Region 1twc A 1082-1091 disorder
       Region 1twc A 1092-1173 order
       Region 1twc A 1174-1176 disorder
       Region 1twc A 1177-1177 order
       Region 1twc A 1178-1186 disorder
       Region 1twc A 1187-1243 order
       Region 1twc A 1244-1253 disorder
       Region 1twc A 1254-1385 order
       Region 1twc A 1386-1404 disorder
       Region 1twc A 1405-1450 order
       Region 1twc A 1451-1733 disorder
 Evidence X-RAY 1twg A Reference
       Region 1twg A 1-2 disorder
       Region 1twg A 3-248 order
       Region 1twg A 249-260 disorder
       Region 1twg A 261-305 order
       Region 1twg A 306-323 disorder
       Region 1twg A 324-327 order
       Region 1twg A 328-345 disorder
       Region 1twg A 346-1081 order
       Region 1twg A 1082-1091 disorder
       Region 1twg A 1092-1173 order
       Region 1twg A 1174-1176 disorder
       Region 1twg A 1177-1177 order
       Region 1twg A 1178-1186 disorder
       Region 1twg A 1187-1243 order
       Region 1twg A 1244-1253 disorder
       Region 1twg A 1254-1385 order
       Region 1twg A 1386-1404 disorder
       Region 1twg A 1405-1450 order
       Region 1twg A 1451-1733 disorder
 Evidence X-RAY 1twh A Reference
       Region 1twh A 1-2 disorder
       Region 1twh A 3-248 order
       Region 1twh A 249-260 disorder
       Region 1twh A 261-305 order
       Region 1twh A 306-323 disorder
       Region 1twh A 324-327 order
       Region 1twh A 328-345 disorder
       Region 1twh A 346-1081 order
       Region 1twh A 1082-1091 disorder
       Region 1twh A 1092-1173 order
       Region 1twh A 1174-1176 disorder
       Region 1twh A 1177-1177 order
       Region 1twh A 1178-1186 disorder
       Region 1twh A 1187-1243 order
       Region 1twh A 1244-1253 disorder
       Region 1twh A 1254-1385 order
       Region 1twh A 1386-1404 disorder
       Region 1twh A 1405-1450 order
       Region 1twh A 1451-1733 disorder
Seq 1-1733 Hetero tridecamer : P08518,P16370,P20433,P20434,P20435,P20436,P27999,P34087,P36106,P38902
 Evidence X-RAY 4bxx A Reference
       Region 4bxx A 1-1 disorder
       Region 4bxx A 2-186 order
       Region 4bxx A 187-194 disorder
       Region 4bxx A 195-1081 order
       Region 4bxx A 1082-1091 disorder
       Region 4bxx A 1092-1246 order
       Region 4bxx A 1247-1253 disorder
       Region 4bxx A 1254-1455 order
       Region 4bxx A 1456-1733 disorder
 Evidence X-RAY 4bxz A Reference
       Region 4bxz A 1-1 disorder
       Region 4bxz A 2-186 order
       Region 4bxz A 187-194 disorder
       Region 4bxz A 195-1081 order
       Region 4bxz A 1082-1091 disorder
       Region 4bxz A 1092-1176 order
       Region 4bxz A 1177-1186 disorder
       Region 4bxz A 1187-1243 order
       Region 4bxz A 1244-1253 disorder
       Region 4bxz A 1254-1455 order
       Region 4bxz A 1456-1733 disorder
 Evidence X-RAY 4by1 A Reference
       Region 4by1 A 1-1 disorder
       Region 4by1 A 2-186 order
       Region 4by1 A 187-194 disorder
       Region 4by1 A 195-1083 order
       Region 4by1 A 1084-1093 disorder
       Region 4by1 A 1094-1244 order
       Region 4by1 A 1245-1253 disorder
       Region 4by1 A 1254-1455 order
       Region 4by1 A 1456-1733 disorder
 Evidence X-RAY 4by7 A Reference
       Region 4by7 A 1-1 disorder
       Region 4by7 A 2-186 order
       Region 4by7 A 187-194 disorder
       Region 4by7 A 195-1082 order
       Region 4by7 A 1083-1093 disorder
       Region 4by7 A 1094-1244 order
       Region 4by7 A 1245-1253 disorder
       Region 4by7 A 1254-1455 order
       Region 4by7 A 1456-1733 disorder
Seq 1-1733 Hetero dodecamer : P08518,P16370,P20433,P20434,P20435,P20436,P27999,P34087,P38902
 Evidence X-RAY 1y1w A Reference
       Region 1y1w A 1-1 disorder
       Region 1y1w A 2-186 order
       Region 1y1w A 187-194 disorder
       Region 1y1w A 195-1081 order
       Region 1y1w A 1082-1091 disorder
       Region 1y1w A 1092-1176 order
       Region 1y1w A 1177-1186 disorder
       Region 1y1w A 1187-1243 order
       Region 1y1w A 1244-1253 disorder
       Region 1y1w A 1254-1455 order
       Region 1y1w A 1456-1733 disorder
 Evidence X-RAY 2b8k A Reference
       Region 2b8k A 1-1 disorder
       Region 2b8k A 2-186 order
       Region 2b8k A 187-194 disorder
       Region 2b8k A 195-1081 order
       Region 2b8k A 1082-1091 disorder
       Region 2b8k A 1092-1176 order
       Region 2b8k A 1177-1186 disorder
       Region 2b8k A 1187-1243 order
       Region 2b8k A 1244-1253 disorder
       Region 2b8k A 1254-1455 order
       Region 2b8k A 1456-1733 disorder
 Evidence X-RAY 2ja7 A Reference
       Region 2ja7 A 1-1 disorder
       Region 2ja7 A 2-189 order
       Region 2ja7 A 190-194 disorder
       Region 2ja7 A 195-1081 order
       Region 2ja7 A 1082-1091 disorder
       Region 2ja7 A 1092-1175 order
       Region 2ja7 A 1176-1176 disorder
       Region 2ja7 A 1177-1177 order
       Region 2ja7 A 1178-1186 disorder
       Region 2ja7 A 1187-1245 order
       Region 2ja7 A 1246-1253 disorder
       Region 2ja7 A 1254-1455 order
       Region 2ja7 A 1456-1733 disorder
 Evidence X-RAY 2ja7 M Reference
       Region 2ja7 M 1-1 disorder
       Region 2ja7 M 2-189 order
       Region 2ja7 M 190-194 disorder
       Region 2ja7 M 195-1081 order
       Region 2ja7 M 1082-1091 disorder
       Region 2ja7 M 1092-1175 order
       Region 2ja7 M 1176-1176 disorder
       Region 2ja7 M 1177-1177 order
       Region 2ja7 M 1178-1186 disorder
       Region 2ja7 M 1187-1245 order
       Region 2ja7 M 1246-1253 disorder
       Region 2ja7 M 1254-1455 order
       Region 2ja7 M 1456-1733 disorder
 Evidence X-RAY 2r92 A Reference
       Region 2r92 A 1-1 disorder
       Region 2r92 A 2-189 order
       Region 2r92 A 190-194 disorder
       Region 2r92 A 195-1081 order
       Region 2r92 A 1082-1091 disorder
       Region 2r92 A 1092-1177 order
       Region 2r92 A 1178-1186 disorder
       Region 2r92 A 1187-1245 order
       Region 2r92 A 1246-1253 disorder
       Region 2r92 A 1254-1455 order
       Region 2r92 A 1456-1733 disorder
 Evidence X-RAY 2r93 A Reference
       Region 2r93 A 1-1 disorder
       Region 2r93 A 2-189 order
       Region 2r93 A 190-194 disorder
       Region 2r93 A 195-1081 order
       Region 2r93 A 1082-1091 disorder
       Region 2r93 A 1092-1177 order
       Region 2r93 A 1178-1186 disorder
       Region 2r93 A 1187-1245 order
       Region 2r93 A 1246-1253 disorder
       Region 2r93 A 1254-1455 order
       Region 2r93 A 1456-1733 disorder
 Evidence X-RAY 3fki A Reference
       Region 3fki A 1-1 disorder
       Region 3fki A 2-1081 order
       Region 3fki A 1082-1090 disorder
       Region 3fki A 1091-1175 order
       Region 3fki A 1176-1184 disorder
       Region 3fki A 1185-1245 order
       Region 3fki A 1246-1253 disorder
       Region 3fki A 1254-1454 order
       Region 3fki A 1455-1733 disorder
 Evidence X-RAY 3h3v B Reference
       Region 3h3v B 1-1 disorder
       Region 3h3v B 2-186 order
       Region 3h3v B 187-194 disorder
       Region 3h3v B 195-1081 order
       Region 3h3v B 1082-1091 disorder
       Region 3h3v B 1092-1176 order
       Region 3h3v B 1177-1186 disorder
       Region 3h3v B 1187-1243 order
       Region 3h3v B 1244-1253 disorder
       Region 3h3v B 1254-1455 order
       Region 3h3v B 1456-1733 disorder
 Evidence X-RAY 3hou A Reference
       Region 3hou A 1-1 disorder
       Region 3hou A 2-186 order
       Region 3hou A 187-194 disorder
       Region 3hou A 195-1081 order
       Region 3hou A 1082-1091 disorder
       Region 3hou A 1092-1175 order
       Region 3hou A 1176-1186 disorder
       Region 3hou A 1187-1244 order
       Region 3hou A 1245-1253 disorder
       Region 3hou A 1254-1455 order
       Region 3hou A 1456-1733 disorder
 Evidence X-RAY 3hou M Reference
       Region 3hou M 1-1 disorder
       Region 3hou M 2-186 order
       Region 3hou M 187-194 disorder
       Region 3hou M 195-1081 order
       Region 3hou M 1082-1091 disorder
       Region 3hou M 1092-1175 order
       Region 3hou M 1176-1186 disorder
       Region 3hou M 1187-1244 order
       Region 3hou M 1245-1253 disorder
       Region 3hou M 1254-1455 order
       Region 3hou M 1456-1733 disorder
 Evidence X-RAY 3hov A Reference
       Region 3hov A 1-1 disorder
       Region 3hov A 2-186 order
       Region 3hov A 187-194 disorder
       Region 3hov A 195-1081 order
       Region 3hov A 1082-1091 disorder
       Region 3hov A 1092-1175 order
       Region 3hov A 1176-1186 disorder
       Region 3hov A 1187-1244 order
       Region 3hov A 1245-1253 disorder
       Region 3hov A 1254-1455 order
       Region 3hov A 1456-1733 disorder
 Evidence X-RAY 3how A Reference
       Region 3how A 1-1 disorder
       Region 3how A 2-186 order
       Region 3how A 187-194 disorder
       Region 3how A 195-1081 order
       Region 3how A 1082-1091 disorder
       Region 3how A 1092-1175 order
       Region 3how A 1176-1186 disorder
       Region 3how A 1187-1244 order
       Region 3how A 1245-1253 disorder
       Region 3how A 1254-1455 order
       Region 3how A 1456-1733 disorder
 Evidence X-RAY 3hox A Reference
       Region 3hox A 1-1 disorder
       Region 3hox A 2-186 order
       Region 3hox A 187-195 disorder
       Region 3hox A 196-1081 order
       Region 3hox A 1082-1091 disorder
       Region 3hox A 1092-1175 order
       Region 3hox A 1176-1186 disorder
       Region 3hox A 1187-1245 order
       Region 3hox A 1246-1252 disorder
       Region 3hox A 1253-1455 order
       Region 3hox A 1456-1733 disorder
 Evidence X-RAY 3hoy A Reference
       Region 3hoy A 1-1 disorder
       Region 3hoy A 2-188 order
       Region 3hoy A 189-195 disorder
       Region 3hoy A 196-1081 order
       Region 3hoy A 1082-1090 disorder
       Region 3hoy A 1091-1176 order
       Region 3hoy A 1177-1186 disorder
       Region 3hoy A 1187-1244 order
       Region 3hoy A 1245-1253 disorder
       Region 3hoy A 1254-1455 order
       Region 3hoy A 1456-1733 disorder
 Evidence X-RAY 3hoz A Reference
       Region 3hoz A 1-1 disorder
       Region 3hoz A 2-187 order
       Region 3hoz A 188-194 disorder
       Region 3hoz A 195-1081 order
       Region 3hoz A 1082-1092 disorder
       Region 3hoz A 1093-1175 order
       Region 3hoz A 1176-1185 disorder
       Region 3hoz A 1186-1245 order
       Region 3hoz A 1246-1253 disorder
       Region 3hoz A 1254-1455 order
       Region 3hoz A 1456-1733 disorder
 Evidence X-RAY 3i4m A Reference
       Region 3i4m A 1-1 disorder
       Region 3i4m A 2-1081 order
       Region 3i4m A 1082-1092 disorder
       Region 3i4m A 1093-1179 order
       Region 3i4m A 1180-1186 disorder
       Region 3i4m A 1187-1246 order
       Region 3i4m A 1247-1253 disorder
       Region 3i4m A 1254-1455 order
       Region 3i4m A 1456-1733 disorder
 Evidence X-RAY 3i4n A Reference
       Region 3i4n A 1-1 disorder
       Region 3i4n A 2-1081 order
       Region 3i4n A 1082-1092 disorder
       Region 3i4n A 1093-1179 order
       Region 3i4n A 1180-1186 disorder
       Region 3i4n A 1187-1246 order
       Region 3i4n A 1247-1253 disorder
       Region 3i4n A 1254-1455 order
       Region 3i4n A 1456-1733 disorder
 Evidence X-RAY 3po2 A Reference
       Region 3po2 A 1-2 disorder
       Region 3po2 A 3-186 order
       Region 3po2 A 187-194 disorder
       Region 3po2 A 195-1086 order
       Region 3po2 A 1087-1090 disorder
       Region 3po2 A 1091-1176 order
       Region 3po2 A 1177-1186 disorder
       Region 3po2 A 1187-1244 order
       Region 3po2 A 1245-1253 disorder
       Region 3po2 A 1254-1454 order
       Region 3po2 A 1455-1733 disorder
 Evidence X-RAY 4a3b A Reference
       Region 4a3b A 1-2 disorder
       Region 4a3b A 3-1080 order
       Region 4a3b A 1081-1091 disorder
       Region 4a3b A 1092-1176 order
       Region 4a3b A 1177-1186 disorder
       Region 4a3b A 1187-1243 order
       Region 4a3b A 1244-1253 disorder
       Region 4a3b A 1254-1455 order
       Region 4a3b A 1456-1732 disorder
 Evidence X-RAY 4a3d A Reference
       Region 4a3d A 1-2 disorder
       Region 4a3d A 3-1080 order
       Region 4a3d A 1081-1091 disorder
       Region 4a3d A 1092-1176 order
       Region 4a3d A 1177-1186 disorder
       Region 4a3d A 1187-1243 order
       Region 4a3d A 1244-1253 disorder
       Region 4a3d A 1254-1455 order
       Region 4a3d A 1456-1732 disorder
 Evidence X-RAY 4a3e A Reference
       Region 4a3e A 1-2 disorder
       Region 4a3e A 3-1081 order
       Region 4a3e A 1082-1091 disorder
       Region 4a3e A 1092-1176 order
       Region 4a3e A 1177-1186 disorder
       Region 4a3e A 1187-1243 order
       Region 4a3e A 1244-1253 disorder
       Region 4a3e A 1254-1455 order
       Region 4a3e A 1456-1732 disorder
 Evidence X-RAY 4a3f A Reference
       Region 4a3f A 1-2 disorder
       Region 4a3f A 3-1083 order
       Region 4a3f A 1084-1091 disorder
       Region 4a3f A 1092-1176 order
       Region 4a3f A 1177-1186 disorder
       Region 4a3f A 1187-1243 order
       Region 4a3f A 1244-1253 disorder
       Region 4a3f A 1254-1455 order
       Region 4a3f A 1456-1732 disorder
 Evidence X-RAY 4a3g A Reference
       Region 4a3g A 1-2 disorder
       Region 4a3g A 3-1080 order
       Region 4a3g A 1081-1091 disorder
       Region 4a3g A 1092-1176 order
       Region 4a3g A 1177-1186 disorder
       Region 4a3g A 1187-1243 order
       Region 4a3g A 1244-1253 disorder
       Region 4a3g A 1254-1455 order
       Region 4a3g A 1456-1732 disorder
 Evidence X-RAY 4a3i A Reference
       Region 4a3i A 1-2 disorder
       Region 4a3i A 3-1080 order
       Region 4a3i A 1081-1091 disorder
       Region 4a3i A 1092-1176 order
       Region 4a3i A 1177-1186 disorder
       Region 4a3i A 1187-1243 order
       Region 4a3i A 1244-1253 disorder
       Region 4a3i A 1254-1455 order
       Region 4a3i A 1456-1732 disorder
 Evidence X-RAY 4a3j A Reference
       Region 4a3j A 1-2 disorder
       Region 4a3j A 3-1083 order
       Region 4a3j A 1084-1091 disorder
       Region 4a3j A 1092-1176 order
       Region 4a3j A 1177-1186 disorder
       Region 4a3j A 1187-1243 order
       Region 4a3j A 1244-1253 disorder
       Region 4a3j A 1254-1455 order
       Region 4a3j A 1456-1732 disorder
 Evidence X-RAY 4a3k A Reference
       Region 4a3k A 1-2 disorder
       Region 4a3k A 3-1080 order
       Region 4a3k A 1081-1091 disorder
       Region 4a3k A 1092-1176 order
       Region 4a3k A 1177-1186 disorder
       Region 4a3k A 1187-1243 order
       Region 4a3k A 1244-1253 disorder
       Region 4a3k A 1254-1455 order
       Region 4a3k A 1456-1732 disorder
 Evidence X-RAY 4a3l A Reference
       Region 4a3l A 1-2 disorder
       Region 4a3l A 3-1083 order
       Region 4a3l A 1084-1091 disorder
       Region 4a3l A 1092-1176 order
       Region 4a3l A 1177-1186 disorder
       Region 4a3l A 1187-1243 order
       Region 4a3l A 1244-1253 disorder
       Region 4a3l A 1254-1455 order
       Region 4a3l A 1456-1732 disorder
 Evidence X-RAY 4a3m A Reference
       Region 4a3m A 1-2 disorder
       Region 4a3m A 3-1083 order
       Region 4a3m A 1084-1091 disorder
       Region 4a3m A 1092-1176 order
       Region 4a3m A 1177-1186 disorder
       Region 4a3m A 1187-1243 order
       Region 4a3m A 1244-1253 disorder
       Region 4a3m A 1254-1455 order
       Region 4a3m A 1456-1732 disorder
 Evidence X-RAY 5c3e A Reference
       Region 5c3e A 1-1 disorder
       Region 5c3e A 2-43 order
       Region 5c3e A 44-44 disorder
       Region 5c3e A 45-1083 order
       Region 5c3e A 1084-1088 disorder
       Region 5c3e A 1089-1175 order
       Region 5c3e A 1176-1184 disorder
       Region 5c3e A 1185-1245 order
       Region 5c3e A 1246-1253 disorder
       Region 5c3e A 1254-1454 order
       Region 5c3e A 1455-1733 disorder
 Evidence X-RAY 5c44 A Reference
       Region 5c44 A 1-1 disorder
       Region 5c44 A 2-1081 order
       Region 5c44 A 1082-1083 disorder
       Region 5c44 A 1084-1175 order
       Region 5c44 A 1176-1184 disorder
       Region 5c44 A 1185-1245 order
       Region 5c44 A 1246-1253 disorder
       Region 5c44 A 1254-1454 order
       Region 5c44 A 1455-1733 disorder
 Evidence X-RAY 5c4x A Reference
       Region 5c4x A 1-1 disorder
       Region 5c4x A 2-1175 order
       Region 5c4x A 1176-1184 disorder
       Region 5c4x A 1185-1245 order
       Region 5c4x A 1246-1253 disorder
       Region 5c4x A 1254-1454 order
       Region 5c4x A 1455-1733 disorder
 Evidence X-RAY 5ot2 A Reference
       Region 5ot2 A 1-3 disorder
       Region 5ot2 A 4-186 order
       Region 5ot2 A 187-194 disorder
       Region 5ot2 A 195-1082 order
       Region 5ot2 A 1083-1091 disorder
       Region 5ot2 A 1092-1174 order
       Region 5ot2 A 1175-1186 disorder
       Region 5ot2 A 1187-1244 order
       Region 5ot2 A 1245-1254 disorder
       Region 5ot2 A 1255-1454 order
       Region 5ot2 A 1455-1733 disorder
 Evidence X-RAY 5u5q A Reference
       Region 5u5q A 1-2 disorder
       Region 5u5q A 3-185 order
       Region 5u5q A 186-194 disorder
       Region 5u5q A 195-1081 order
       Region 5u5q A 1082-1091 disorder
       Region 5u5q A 1092-1455 order
       Region 5u5q A 1456-1733 disorder
Seq 1-1733 Hetero tridecamer : P08518,P16370,P20433,P20434,P20435,P20436,P27999,P34087,P38902,P85421
 Evidence X-RAY 2vum A Reference
       Region 2vum A 1-1 disorder
       Region 2vum A 2-186 order
       Region 2vum A 187-194 disorder
       Region 2vum A 195-1085 order
       Region 2vum A 1086-1093 disorder
       Region 2vum A 1094-1176 order
       Region 2vum A 1177-1186 disorder
       Region 2vum A 1187-1243 order
       Region 2vum A 1244-1253 disorder
       Region 2vum A 1254-1455 order
       Region 2vum A 1456-1733 disorder
Seq 1-1733 Hetero dodecamer : P08518,P16370,P20434,P20435,P20436,P27999,P34087,P38902
 Evidence X-RAY 5c4a A Reference
       Region 5c4a A 1-1 disorder
       Region 5c4a A 2-1081 order
       Region 5c4a A 1082-1092 disorder
       Region 5c4a A 1093-1175 order
       Region 5c4a A 1176-1184 disorder
       Region 5c4a A 1185-1245 order
       Region 5c4a A 1246-1253 disorder
       Region 5c4a A 1254-1454 order
       Region 5c4a A 1455-1733 disorder
Seq 1-1733 Hetero tridecamer : P07273,P08518,P16370,P20434,P20435,P20436,P27999,P34087,P38902
 Evidence X-RAY 1pqv A Reference
       Region 1pqv A 1-1 disorder
       Region 1pqv A 2-154 order
       Region 1pqv A 155-160 disorder
       Region 1pqv A 161-186 order
       Region 1pqv A 187-198 disorder
       Region 1pqv A 199-249 order
       Region 1pqv A 250-258 disorder
       Region 1pqv A 259-314 order
       Region 1pqv A 315-320 disorder
       Region 1pqv A 321-1243 order
       Region 1pqv A 1244-1253 disorder
       Region 1pqv A 1254-1453 order
       Region 1pqv A 1454-1733 disorder
Seq 1-1733 Hetero tridecamer : P07273,P08518,P16370,P20433,P20434,P20435,P20436,P27999,P34087,P38902
 Evidence X-RAY 3po3 A Reference
       Region 3po3 A 1-1 disorder
       Region 3po3 A 2-186 order
       Region 3po3 A 187-194 disorder
       Region 3po3 A 195-1176 order
       Region 3po3 A 1177-1186 disorder
       Region 3po3 A 1187-1243 order
       Region 3po3 A 1244-1253 disorder
       Region 3po3 A 1254-1455 order
       Region 3po3 A 1456-1733 disorder
Seq 1-1733 Hetero dodecamer : P08518,P16370,P20433,P20434,P20435,P20436,P27999,P34087,P38902
 Evidence X-RAY 1wcm A Reference
       Region 1wcm A 1-1 disorder
       Region 1wcm A 2-186 order
       Region 1wcm A 187-194 disorder
       Region 1wcm A 195-1081 order
       Region 1wcm A 1082-1091 disorder
       Region 1wcm A 1092-1176 order
       Region 1wcm A 1177-1186 disorder
       Region 1wcm A 1187-1243 order
       Region 1wcm A 1244-1253 disorder
       Region 1wcm A 1254-1455 order
       Region 1wcm A 1456-1733 disorder
 Evidence X-RAY 1y77 A Reference
       Region 1y77 A 1-1 disorder
       Region 1y77 A 2-186 order
       Region 1y77 A 187-194 disorder
       Region 1y77 A 195-1081 order
       Region 1y77 A 1082-1091 disorder
       Region 1y77 A 1092-1176 order
       Region 1y77 A 1177-1186 disorder
       Region 1y77 A 1187-1243 order
       Region 1y77 A 1244-1253 disorder
       Region 1y77 A 1254-1455 order
       Region 1y77 A 1456-1733 disorder
 Evidence X-RAY 2ja5 A Reference
       Region 2ja5 A 1-1 disorder
       Region 2ja5 A 2-189 order
       Region 2ja5 A 190-194 disorder
       Region 2ja5 A 195-1081 order
       Region 2ja5 A 1082-1091 disorder
       Region 2ja5 A 1092-1175 order
       Region 2ja5 A 1176-1176 disorder
       Region 2ja5 A 1177-1177 order
       Region 2ja5 A 1178-1186 disorder
       Region 2ja5 A 1187-1245 order
       Region 2ja5 A 1246-1253 disorder
       Region 2ja5 A 1254-1455 order
       Region 2ja5 A 1456-1733 disorder
 Evidence X-RAY 2ja6 A Reference
       Region 2ja6 A 1-1 disorder
       Region 2ja6 A 2-189 order
       Region 2ja6 A 190-194 disorder
       Region 2ja6 A 195-1081 order
       Region 2ja6 A 1082-1091 disorder
       Region 2ja6 A 1092-1175 order
       Region 2ja6 A 1176-1176 disorder
       Region 2ja6 A 1177-1177 order
       Region 2ja6 A 1178-1186 disorder
       Region 2ja6 A 1187-1245 order
       Region 2ja6 A 1246-1253 disorder
       Region 2ja6 A 1254-1455 order
       Region 2ja6 A 1456-1733 disorder
 Evidence X-RAY 2ja8 A Reference
       Region 2ja8 A 1-1 disorder
       Region 2ja8 A 2-189 order
       Region 2ja8 A 190-194 disorder
       Region 2ja8 A 195-1081 order
       Region 2ja8 A 1082-1091 disorder
       Region 2ja8 A 1092-1175 order
       Region 2ja8 A 1176-1176 disorder
       Region 2ja8 A 1177-1177 order
       Region 2ja8 A 1178-1186 disorder
       Region 2ja8 A 1187-1245 order
       Region 2ja8 A 1246-1253 disorder
       Region 2ja8 A 1254-1455 order
       Region 2ja8 A 1456-1733 disorder
 Evidence X-RAY 2r7z A Reference
       Region 2r7z A 1-1 disorder
       Region 2r7z A 2-186 order
       Region 2r7z A 187-194 disorder
       Region 2r7z A 195-1081 order
       Region 2r7z A 1082-1091 disorder
       Region 2r7z A 1092-1176 order
       Region 2r7z A 1177-1186 disorder
       Region 2r7z A 1187-1243 order
       Region 2r7z A 1244-1253 disorder
       Region 2r7z A 1254-1455 order
       Region 2r7z A 1456-1733 disorder
Seq 1-1733 Hetero tridecamer : P07273,P08518,P16370,P20433,P20434,P20435,P20436,P27999,P34087,P38902
 Evidence X-RAY 1y1v A Reference
       Region 1y1v A 1-1 disorder
       Region 1y1v A 2-186 order
       Region 1y1v A 187-194 disorder
       Region 1y1v A 195-1176 order
       Region 1y1v A 1177-1186 disorder
       Region 1y1v A 1187-1243 order
       Region 1y1v A 1244-1253 disorder
       Region 1y1v A 1254-1455 order
       Region 1y1v A 1456-1733 disorder
 Evidence X-RAY 1y1y A Reference
       Region 1y1y A 1-1 disorder
       Region 1y1y A 2-186 order
       Region 1y1y A 187-194 disorder
       Region 1y1y A 195-1176 order
       Region 1y1y A 1177-1186 disorder
       Region 1y1y A 1187-1243 order
       Region 1y1y A 1244-1253 disorder
       Region 1y1y A 1254-1455 order
       Region 1y1y A 1456-1733 disorder
Seq 1-1733 Hetero tridecamer : P08518,P16370,P20433,P20434,P20435,P20436,P27999,P29055,P34087,P38902
 Evidence X-RAY 3k1f A Reference
       Region 3k1f A 1-1 disorder
       Region 3k1f A 2-186 order
       Region 3k1f A 187-194 disorder
       Region 3k1f A 195-1081 order
       Region 3k1f A 1082-1091 disorder
       Region 3k1f A 1092-1175 order
       Region 3k1f A 1176-1186 disorder
       Region 3k1f A 1187-1244 order
       Region 3k1f A 1245-1253 disorder
       Region 3k1f A 1254-1455 order
       Region 3k1f A 1456-1733 disorder
Seq 1-1733 Hetero decamer : P08518,P16370,P20434,P20435,P20436,P27999,P38902
 Evidence X-RAY 1i3q A Reference
       Region 1i3q A 1-1 disorder
       Region 1i3q A 2-1081 order
       Region 1i3q A 1082-1091 disorder
       Region 1i3q A 1092-1176 order
       Region 1i3q A 1177-1186 disorder
       Region 1i3q A 1187-1243 order
       Region 1i3q A 1244-1253 disorder
       Region 1i3q A 1254-1445 order
       Region 1i3q A 1446-1733 disorder
 Evidence X-RAY 1i50 A Reference
       Region 1i50 A 1-1 disorder
       Region 1i50 A 2-1081 order
       Region 1i50 A 1082-1091 disorder
       Region 1i50 A 1092-1176 order
       Region 1i50 A 1177-1186 disorder
       Region 1i50 A 1187-1243 order
       Region 1i50 A 1244-1253 disorder
       Region 1i50 A 1254-1450 order
       Region 1i50 A 1451-1733 disorder
 Evidence X-RAY 1i6h A Reference
       Region 1i6h A 1-1 disorder
       Region 1i6h A 2-154 order
       Region 1i6h A 155-160 disorder
       Region 1i6h A 161-186 order
       Region 1i6h A 187-198 disorder
       Region 1i6h A 199-249 order
       Region 1i6h A 250-258 disorder
       Region 1i6h A 259-314 order
       Region 1i6h A 315-320 disorder
       Region 1i6h A 321-1081 order
       Region 1i6h A 1082-1091 disorder
       Region 1i6h A 1092-1176 order
       Region 1i6h A 1177-1186 disorder
       Region 1i6h A 1187-1243 order
       Region 1i6h A 1244-1253 disorder
       Region 1i6h A 1254-1445 order
       Region 1i6h A 1446-1733 disorder
 Evidence X-RAY 1nik A Reference
       Region 1nik A 1-1 disorder
       Region 1nik A 2-154 order
       Region 1nik A 155-160 disorder
       Region 1nik A 161-186 order
       Region 1nik A 187-198 disorder
       Region 1nik A 199-249 order
       Region 1nik A 250-258 disorder
       Region 1nik A 259-314 order
       Region 1nik A 315-320 disorder
       Region 1nik A 321-1081 order
       Region 1nik A 1082-1091 disorder
       Region 1nik A 1092-1176 order
       Region 1nik A 1177-1186 disorder
       Region 1nik A 1187-1243 order
       Region 1nik A 1244-1253 disorder
       Region 1nik A 1254-1452 order
       Region 1nik A 1453-1733 disorder
 Evidence X-RAY 1r5u A Reference
       Region 1r5u A 1-1 disorder
       Region 1r5u A 2-154 order
       Region 1r5u A 155-160 disorder
       Region 1r5u A 161-186 order
       Region 1r5u A 187-198 disorder
       Region 1r5u A 199-249 order
       Region 1r5u A 250-258 disorder
       Region 1r5u A 259-314 order
       Region 1r5u A 315-320 disorder
       Region 1r5u A 321-808 order
       Region 1r5u A 809-809 disorder
       Region 1r5u A 810-1081 order
       Region 1r5u A 1082-1091 disorder
       Region 1r5u A 1092-1176 order
       Region 1r5u A 1177-1186 disorder
       Region 1r5u A 1187-1243 order
       Region 1r5u A 1244-1253 disorder
       Region 1r5u A 1254-1445 order
       Region 1r5u A 1446-1733 disorder
 Evidence X-RAY 1r9s A Reference
       Region 1r9s A 1-1 disorder
       Region 1r9s A 2-154 order
       Region 1r9s A 155-160 disorder
       Region 1r9s A 161-186 order
       Region 1r9s A 187-198 disorder
       Region 1r9s A 199-249 order
       Region 1r9s A 250-258 disorder
       Region 1r9s A 259-314 order
       Region 1r9s A 315-320 disorder
       Region 1r9s A 321-1081 order
       Region 1r9s A 1082-1091 disorder
       Region 1r9s A 1092-1176 order
       Region 1r9s A 1177-1186 disorder
       Region 1r9s A 1187-1243 order
       Region 1r9s A 1244-1253 disorder
       Region 1r9s A 1254-1445 order
       Region 1r9s A 1446-1733 disorder
 Evidence X-RAY 1r9t A Reference
       Region 1r9t A 1-2 disorder
       Region 1r9t A 3-154 order
       Region 1r9t A 155-160 disorder
       Region 1r9t A 161-185 order
       Region 1r9t A 186-186 disorder
       Region 1r9t A 187-187 order
       Region 1r9t A 188-198 disorder
       Region 1r9t A 199-1081 order
       Region 1r9t A 1082-1091 disorder
       Region 1r9t A 1092-1175 order
       Region 1r9t A 1176-1176 disorder
       Region 1r9t A 1177-1177 order
       Region 1r9t A 1178-1186 disorder
       Region 1r9t A 1187-1243 order
       Region 1r9t A 1244-1253 disorder
       Region 1r9t A 1254-1445 order
       Region 1r9t A 1446-1733 disorder
 Evidence X-RAY 1sfo A Reference
       Region 1sfo A 1-2 disorder
       Region 1sfo A 3-154 order
       Region 1sfo A 155-160 disorder
       Region 1sfo A 161-186 order
       Region 1sfo A 187-198 disorder
       Region 1sfo A 199-1081 order
       Region 1sfo A 1082-1091 disorder
       Region 1sfo A 1092-1176 order
       Region 1sfo A 1177-1186 disorder
       Region 1sfo A 1187-1243 order
       Region 1sfo A 1244-1253 disorder
       Region 1sfo A 1254-1445 order
       Region 1sfo A 1446-1733 disorder
 Evidence X-RAY 1twf A Reference
       Region 1twf A 1-1 disorder
       Region 1twf A 2-1081 order
       Region 1twf A 1082-1091 disorder
       Region 1twf A 1092-1176 order
       Region 1twf A 1177-1186 disorder
       Region 1twf A 1187-1243 order
       Region 1twf A 1244-1253 disorder
       Region 1twf A 1254-1450 order
       Region 1twf A 1451-1733 disorder
 Evidence X-RAY 2e2h A Reference
       Region 2e2h A 1-1 disorder
       Region 2e2h A 2-155 order
       Region 2e2h A 156-160 disorder
       Region 2e2h A 161-185 order
       Region 2e2h A 186-198 disorder
       Region 2e2h A 199-314 order
       Region 2e2h A 315-318 disorder
       Region 2e2h A 319-1176 order
       Region 2e2h A 1177-1186 disorder
       Region 2e2h A 1187-1231 order
       Region 2e2h A 1232-1235 disorder
       Region 2e2h A 1236-1243 order
       Region 2e2h A 1244-1253 disorder
       Region 2e2h A 1254-1445 order
       Region 2e2h A 1446-1733 disorder
 Evidence X-RAY 2e2i A Reference
       Region 2e2i A 1-2 disorder
       Region 2e2i A 3-191 order
       Region 2e2i A 192-197 disorder
       Region 2e2i A 198-1081 order
       Region 2e2i A 1082-1091 disorder
       Region 2e2i A 1092-1176 order
       Region 2e2i A 1177-1186 disorder
       Region 2e2i A 1187-1243 order
       Region 2e2i A 1244-1253 disorder
       Region 2e2i A 1254-1449 order
       Region 2e2i A 1450-1733 disorder
 Evidence X-RAY 2e2j A Reference
       Region 2e2j A 1-2 disorder
       Region 2e2j A 3-154 order
       Region 2e2j A 155-160 disorder
       Region 2e2j A 161-186 order
       Region 2e2j A 187-198 disorder
       Region 2e2j A 199-1081 order
       Region 2e2j A 1082-1091 disorder
       Region 2e2j A 1092-1176 order
       Region 2e2j A 1177-1186 disorder
       Region 2e2j A 1187-1243 order
       Region 2e2j A 1244-1253 disorder
       Region 2e2j A 1254-1445 order
       Region 2e2j A 1446-1733 disorder
 Evidence X-RAY 2nvq A Reference
       Region 2nvq A 1-2 disorder
       Region 2nvq A 3-154 order
       Region 2nvq A 155-160 disorder
       Region 2nvq A 161-186 order
       Region 2nvq A 187-198 disorder
       Region 2nvq A 199-1176 order
       Region 2nvq A 1177-1186 disorder
       Region 2nvq A 1187-1243 order
       Region 2nvq A 1244-1253 disorder
       Region 2nvq A 1254-1445 order
       Region 2nvq A 1446-1733 disorder
 Evidence X-RAY 2nvt A Reference
       Region 2nvt A 1-2 disorder
       Region 2nvt A 3-154 order
       Region 2nvt A 155-160 disorder
       Region 2nvt A 161-186 order
       Region 2nvt A 187-198 disorder
       Region 2nvt A 199-1176 order
       Region 2nvt A 1177-1186 disorder
       Region 2nvt A 1187-1243 order
       Region 2nvt A 1244-1253 disorder
       Region 2nvt A 1254-1451 order
       Region 2nvt A 1452-1733 disorder
 Evidence X-RAY 2nvx A Reference
       Region 2nvx A 1-2 disorder
       Region 2nvx A 3-186 order
       Region 2nvx A 187-198 disorder
       Region 2nvx A 199-1081 order
       Region 2nvx A 1082-1091 disorder
       Region 2nvx A 1092-1176 order
       Region 2nvx A 1177-1186 disorder
       Region 2nvx A 1187-1244 order
       Region 2nvx A 1245-1253 disorder
       Region 2nvx A 1254-1445 order
       Region 2nvx A 1446-1733 disorder
 Evidence X-RAY 2nvy A Reference
       Region 2nvy A 1-1 disorder
       Region 2nvy A 2-1081 order
       Region 2nvy A 1082-1091 disorder
       Region 2nvy A 1092-1176 order
       Region 2nvy A 1177-1186 disorder
       Region 2nvy A 1187-1243 order
       Region 2nvy A 1244-1253 disorder
       Region 2nvy A 1254-1450 order
       Region 2nvy A 1451-1733 disorder
 Evidence X-RAY 2nvz A Reference
       Region 2nvz A 1-1 disorder
       Region 2nvz A 2-155 order
       Region 2nvz A 156-160 disorder
       Region 2nvz A 161-185 order
       Region 2nvz A 186-198 disorder
       Region 2nvz A 199-314 order
       Region 2nvz A 315-318 disorder
       Region 2nvz A 319-1176 order
       Region 2nvz A 1177-1186 disorder
       Region 2nvz A 1187-1231 order
       Region 2nvz A 1232-1235 disorder
       Region 2nvz A 1236-1243 order
       Region 2nvz A 1244-1253 disorder
       Region 2nvz A 1254-1445 order
       Region 2nvz A 1446-1733 disorder
 Evidence X-RAY 2yu9 A Reference
       Region 2yu9 A 1-2 disorder
       Region 2yu9 A 3-154 order
       Region 2yu9 A 155-160 disorder
       Region 2yu9 A 161-186 order
       Region 2yu9 A 187-198 disorder
       Region 2yu9 A 199-1176 order
       Region 2yu9 A 1177-1186 disorder
       Region 2yu9 A 1187-1244 order
       Region 2yu9 A 1245-1253 disorder
       Region 2yu9 A 1254-1450 order
       Region 2yu9 A 1451-1733 disorder
 Evidence X-RAY 3gtg A Reference
       Region 3gtg A 1-2 disorder
       Region 3gtg A 3-1179 order
       Region 3gtg A 1180-1186 disorder
       Region 3gtg A 1187-1451 order
       Region 3gtg A 1452-1733 disorder
 Evidence X-RAY 3gtj A Reference
       Region 3gtj A 1-2 disorder
       Region 3gtj A 3-155 order
       Region 3gtj A 156-159 disorder
       Region 3gtj A 160-1085 order
       Region 3gtj A 1086-1088 disorder
       Region 3gtj A 1089-1179 order
       Region 3gtj A 1180-1186 disorder
       Region 3gtj A 1187-1246 order
       Region 3gtj A 1247-1252 disorder
       Region 3gtj A 1253-1451 order
       Region 3gtj A 1452-1733 disorder
 Evidence X-RAY 3gtk A Reference
       Region 3gtk A 1-2 disorder
       Region 3gtk A 3-1179 order
       Region 3gtk A 1180-1186 disorder
       Region 3gtk A 1187-1451 order
       Region 3gtk A 1452-1733 disorder
 Evidence X-RAY 3gtl A Reference
       Region 3gtl A 1-2 disorder
       Region 3gtl A 3-154 order
       Region 3gtl A 155-160 disorder
       Region 3gtl A 161-186 order
       Region 3gtl A 187-198 disorder
       Region 3gtl A 199-1081 order
       Region 3gtl A 1082-1091 disorder
       Region 3gtl A 1092-1176 order
       Region 3gtl A 1177-1186 disorder
       Region 3gtl A 1187-1243 order
       Region 3gtl A 1244-1253 disorder
       Region 3gtl A 1254-1445 order
       Region 3gtl A 1446-1733 disorder
 Evidence X-RAY 3gto A Reference
       Region 3gto A 1-2 disorder
       Region 3gto A 3-154 order
       Region 3gto A 155-160 disorder
       Region 3gto A 161-186 order
       Region 3gto A 187-198 disorder
       Region 3gto A 199-1081 order
       Region 3gto A 1082-1091 disorder
       Region 3gto A 1092-1176 order
       Region 3gto A 1177-1186 disorder
       Region 3gto A 1187-1243 order
       Region 3gto A 1244-1253 disorder
       Region 3gto A 1254-1445 order
       Region 3gto A 1446-1733 disorder
 Evidence X-RAY 3gtp A Reference
       Region 3gtp A 1-2 disorder
       Region 3gtp A 3-154 order
       Region 3gtp A 155-160 disorder
       Region 3gtp A 161-186 order
       Region 3gtp A 187-198 disorder
       Region 3gtp A 199-1081 order
       Region 3gtp A 1082-1091 disorder
       Region 3gtp A 1092-1176 order
       Region 3gtp A 1177-1186 disorder
       Region 3gtp A 1187-1243 order
       Region 3gtp A 1244-1253 disorder
       Region 3gtp A 1254-1445 order
       Region 3gtp A 1446-1733 disorder
 Evidence X-RAY 3gtq A Reference
       Region 3gtq A 1-2 disorder
       Region 3gtq A 3-154 order
       Region 3gtq A 155-160 disorder
       Region 3gtq A 161-186 order
       Region 3gtq A 187-198 disorder
       Region 3gtq A 199-1081 order
       Region 3gtq A 1082-1091 disorder
       Region 3gtq A 1092-1176 order
       Region 3gtq A 1177-1186 disorder
       Region 3gtq A 1187-1243 order
       Region 3gtq A 1244-1253 disorder
       Region 3gtq A 1254-1445 order
       Region 3gtq A 1446-1733 disorder
 Evidence X-RAY 3m3y A Reference
       Region 3m3y A 1-2 disorder
       Region 3m3y A 3-154 order
       Region 3m3y A 155-160 disorder
       Region 3m3y A 161-186 order
       Region 3m3y A 187-198 disorder
       Region 3m3y A 199-1081 order
       Region 3m3y A 1082-1091 disorder
       Region 3m3y A 1092-1176 order
       Region 3m3y A 1177-1186 disorder
       Region 3m3y A 1187-1243 order
       Region 3m3y A 1244-1253 disorder
       Region 3m3y A 1254-1445 order
       Region 3m3y A 1446-1733 disorder
 Evidence X-RAY 3m4o A Reference
       Region 3m4o A 1-2 disorder
       Region 3m4o A 3-154 order
       Region 3m4o A 155-160 disorder
       Region 3m4o A 161-186 order
       Region 3m4o A 187-198 disorder
       Region 3m4o A 199-1081 order
       Region 3m4o A 1082-1091 disorder
       Region 3m4o A 1092-1176 order
       Region 3m4o A 1177-1186 disorder
       Region 3m4o A 1187-1243 order
       Region 3m4o A 1244-1253 disorder
       Region 3m4o A 1254-1445 order
       Region 3m4o A 1446-1733 disorder
 Evidence X-RAY 3rzd A Reference
       Region 3rzd A 1-2 disorder
       Region 3rzd A 3-154 order
       Region 3rzd A 155-160 disorder
       Region 3rzd A 161-186 order
       Region 3rzd A 187-198 disorder
       Region 3rzd A 199-1176 order
       Region 3rzd A 1177-1186 disorder
       Region 3rzd A 1187-1243 order
       Region 3rzd A 1244-1253 disorder
       Region 3rzd A 1254-1445 order
       Region 3rzd A 1446-1733 disorder
 Evidence X-RAY 3rzo A Reference
       Region 3rzo A 1-2 disorder
       Region 3rzo A 3-154 order
       Region 3rzo A 155-160 disorder
       Region 3rzo A 161-186 order
       Region 3rzo A 187-198 disorder
       Region 3rzo A 199-1176 order
       Region 3rzo A 1177-1186 disorder
       Region 3rzo A 1187-1243 order
       Region 3rzo A 1244-1253 disorder
       Region 3rzo A 1254-1445 order
       Region 3rzo A 1446-1733 disorder
 Evidence X-RAY 3s14 A Reference
       Region 3s14 A 1-2 disorder
       Region 3s14 A 3-154 order
       Region 3s14 A 155-160 disorder
       Region 3s14 A 161-186 order
       Region 3s14 A 187-198 disorder
       Region 3s14 A 199-1176 order
       Region 3s14 A 1177-1186 disorder
       Region 3s14 A 1187-1243 order
       Region 3s14 A 1244-1253 disorder
       Region 3s14 A 1254-1445 order
       Region 3s14 A 1446-1733 disorder
 Evidence X-RAY 3s15 A Reference
       Region 3s15 A 1-2 disorder
       Region 3s15 A 3-154 order
       Region 3s15 A 155-160 disorder
       Region 3s15 A 161-186 order
       Region 3s15 A 187-198 disorder
       Region 3s15 A 199-1176 order
       Region 3s15 A 1177-1186 disorder
       Region 3s15 A 1187-1243 order
       Region 3s15 A 1244-1253 disorder
       Region 3s15 A 1254-1445 order
       Region 3s15 A 1446-1733 disorder
 Evidence X-RAY 3s16 A Reference
       Region 3s16 A 1-2 disorder
       Region 3s16 A 3-154 order
       Region 3s16 A 155-160 disorder
       Region 3s16 A 161-186 order
       Region 3s16 A 187-198 disorder
       Region 3s16 A 199-1176 order
       Region 3s16 A 1177-1186 disorder
       Region 3s16 A 1187-1243 order
       Region 3s16 A 1244-1253 disorder
       Region 3s16 A 1254-1445 order
       Region 3s16 A 1446-1733 disorder
 Evidence X-RAY 3s17 A Reference
       Region 3s17 A 1-2 disorder
       Region 3s17 A 3-154 order
       Region 3s17 A 155-160 disorder
       Region 3s17 A 161-186 order
       Region 3s17 A 187-198 disorder
       Region 3s17 A 199-1176 order
       Region 3s17 A 1177-1186 disorder
       Region 3s17 A 1187-1243 order
       Region 3s17 A 1244-1253 disorder
       Region 3s17 A 1254-1445 order
       Region 3s17 A 1446-1733 disorder
 Evidence X-RAY 3s1m A Reference
       Region 3s1m A 1-2 disorder
       Region 3s1m A 3-154 order
       Region 3s1m A 155-160 disorder
       Region 3s1m A 161-186 order
       Region 3s1m A 187-198 disorder
       Region 3s1m A 199-1176 order
       Region 3s1m A 1177-1186 disorder
       Region 3s1m A 1187-1243 order
       Region 3s1m A 1244-1253 disorder
       Region 3s1m A 1254-1445 order
       Region 3s1m A 1446-1733 disorder
 Evidence X-RAY 3s1n A Reference
       Region 3s1n A 1-2 disorder
       Region 3s1n A 3-154 order
       Region 3s1n A 155-160 disorder
       Region 3s1n A 161-186 order
       Region 3s1n A 187-198 disorder
       Region 3s1n A 199-1176 order
       Region 3s1n A 1177-1186 disorder
       Region 3s1n A 1187-1243 order
       Region 3s1n A 1244-1253 disorder
       Region 3s1n A 1254-1445 order
       Region 3s1n A 1446-1733 disorder
 Evidence X-RAY 3s1q A Reference
       Region 3s1q A 1-2 disorder
       Region 3s1q A 3-154 order
       Region 3s1q A 155-160 disorder
       Region 3s1q A 161-186 order
       Region 3s1q A 187-198 disorder
       Region 3s1q A 199-1176 order
       Region 3s1q A 1177-1186 disorder
       Region 3s1q A 1187-1243 order
       Region 3s1q A 1244-1253 disorder
       Region 3s1q A 1254-1445 order
       Region 3s1q A 1446-1733 disorder
 Evidence X-RAY 3s1r A Reference
       Region 3s1r A 1-2 disorder
       Region 3s1r A 3-154 order
       Region 3s1r A 155-160 disorder
       Region 3s1r A 161-186 order
       Region 3s1r A 187-198 disorder
       Region 3s1r A 199-1176 order
       Region 3s1r A 1177-1186 disorder
       Region 3s1r A 1187-1243 order
       Region 3s1r A 1244-1253 disorder
       Region 3s1r A 1254-1445 order
       Region 3s1r A 1446-1733 disorder
 Evidence X-RAY 3s2d A Reference
       Region 3s2d A 1-2 disorder
       Region 3s2d A 3-154 order
       Region 3s2d A 155-160 disorder
       Region 3s2d A 161-186 order
       Region 3s2d A 187-198 disorder
       Region 3s2d A 199-1176 order
       Region 3s2d A 1177-1186 disorder
       Region 3s2d A 1187-1243 order
       Region 3s2d A 1244-1253 disorder
       Region 3s2d A 1254-1445 order
       Region 3s2d A 1446-1733 disorder
 Evidence X-RAY 3s2h A Reference
       Region 3s2h A 1-2 disorder
       Region 3s2h A 3-154 order
       Region 3s2h A 155-160 disorder
       Region 3s2h A 161-186 order
       Region 3s2h A 187-198 disorder
       Region 3s2h A 199-1176 order
       Region 3s2h A 1177-1186 disorder
       Region 3s2h A 1187-1243 order
       Region 3s2h A 1244-1253 disorder
       Region 3s2h A 1254-1445 order
       Region 3s2h A 1446-1733 disorder
 Evidence X-RAY 4x67 A Reference
       Region 4x67 A 1-2 disorder
       Region 4x67 A 3-154 order
       Region 4x67 A 155-160 disorder
       Region 4x67 A 161-186 order
       Region 4x67 A 187-198 disorder
       Region 4x67 A 199-1081 order
       Region 4x67 A 1082-1091 disorder
       Region 4x67 A 1092-1175 order
       Region 4x67 A 1176-1186 disorder
       Region 4x67 A 1187-1243 order
       Region 4x67 A 1244-1253 disorder
       Region 4x67 A 1254-1445 order
       Region 4x67 A 1446-1733 disorder
 Evidence X-RAY 4x6a A Reference
       Region 4x6a A 1-2 disorder
       Region 4x6a A 3-154 order
       Region 4x6a A 155-160 disorder
       Region 4x6a A 161-186 order
       Region 4x6a A 187-198 disorder
       Region 4x6a A 199-1081 order
       Region 4x6a A 1082-1091 disorder
       Region 4x6a A 1092-1176 order
       Region 4x6a A 1177-1186 disorder
       Region 4x6a A 1187-1243 order
       Region 4x6a A 1244-1253 disorder
       Region 4x6a A 1254-1445 order
       Region 4x6a A 1446-1733 disorder
 Evidence X-RAY 4y52 A Reference
       Region 4y52 A 1-2 disorder
       Region 4y52 A 3-148 order
       Region 4y52 A 149-150 disorder
       Region 4y52 A 151-154 order
       Region 4y52 A 155-160 disorder
       Region 4y52 A 161-186 order
       Region 4y52 A 187-198 disorder
       Region 4y52 A 199-1081 order
       Region 4y52 A 1082-1091 disorder
       Region 4y52 A 1092-1176 order
       Region 4y52 A 1177-1186 disorder
       Region 4y52 A 1187-1243 order
       Region 4y52 A 1244-1253 disorder
       Region 4y52 A 1254-1445 order
       Region 4y52 A 1446-1733 disorder
 Evidence X-RAY 4y7n A Reference
       Region 4y7n A 1-2 disorder
       Region 4y7n A 3-148 order
       Region 4y7n A 149-150 disorder
       Region 4y7n A 151-154 order
       Region 4y7n A 155-160 disorder
       Region 4y7n A 161-186 order
       Region 4y7n A 187-198 disorder
       Region 4y7n A 199-1081 order
       Region 4y7n A 1082-1091 disorder
       Region 4y7n A 1092-1176 order
       Region 4y7n A 1177-1186 disorder
       Region 4y7n A 1187-1243 order
       Region 4y7n A 1244-1253 disorder
       Region 4y7n A 1254-1445 order
       Region 4y7n A 1446-1733 disorder
 Evidence X-RAY 5c4j A Reference
       Region 5c4j A 1-1 disorder
       Region 5c4j A 2-34 order
       Region 5c4j A 35-35 disorder
       Region 5c4j A 36-43 order
       Region 5c4j A 44-48 disorder
       Region 5c4j A 49-82 order
       Region 5c4j A 83-84 disorder
       Region 5c4j A 85-1243 order
       Region 5c4j A 1244-1255 disorder
       Region 5c4j A 1256-1453 order
       Region 5c4j A 1454-1733 disorder
 Evidence X-RAY 5w4u A Reference
       Region 5w4u A 1-2 disorder
       Region 5w4u A 3-148 order
       Region 5w4u A 149-166 disorder
       Region 5w4u A 167-185 order
       Region 5w4u A 186-200 disorder
       Region 5w4u A 201-252 order
       Region 5w4u A 253-258 disorder
       Region 5w4u A 259-1079 order
       Region 5w4u A 1080-1092 disorder
       Region 5w4u A 1093-1175 order
       Region 5w4u A 1176-1186 disorder
       Region 5w4u A 1187-1243 order
       Region 5w4u A 1244-1256 disorder
       Region 5w4u A 1257-1449 order
       Region 5w4u A 1450-1733 disorder
 Evidence X-RAY 5w51 A Reference
       Region 5w51 A 1-2 disorder
       Region 5w51 A 3-148 order
       Region 5w51 A 149-166 disorder
       Region 5w51 A 167-185 order
       Region 5w51 A 186-200 disorder
       Region 5w51 A 201-252 order
       Region 5w51 A 253-258 disorder
       Region 5w51 A 259-1079 order
       Region 5w51 A 1080-1092 disorder
       Region 5w51 A 1093-1175 order
       Region 5w51 A 1176-1186 disorder
       Region 5w51 A 1187-1243 order
       Region 5w51 A 1244-1256 disorder
       Region 5w51 A 1257-1449 order
       Region 5w51 A 1450-1733 disorder
 Evidence X-RAY 6blo A Reference
       Region 6blo A 1-2 disorder
       Region 6blo A 3-148 order
       Region 6blo A 149-164 disorder
       Region 6blo A 165-185 order
       Region 6blo A 186-200 disorder
       Region 6blo A 201-250 order
       Region 6blo A 251-258 disorder
       Region 6blo A 259-1080 order
       Region 6blo A 1081-1092 disorder
       Region 6blo A 1093-1175 order
       Region 6blo A 1176-1186 disorder
       Region 6blo A 1187-1243 order
       Region 6blo A 1244-1253 disorder
       Region 6blo A 1254-1446 order
       Region 6blo A 1447-1733 disorder
 Evidence X-RAY 6blp A Reference
       Region 6blp A 1-2 disorder
       Region 6blp A 3-148 order
       Region 6blp A 149-164 disorder
       Region 6blp A 165-185 order
       Region 6blp A 186-200 disorder
       Region 6blp A 201-250 order
       Region 6blp A 251-258 disorder
       Region 6blp A 259-1080 order
       Region 6blp A 1081-1092 disorder
       Region 6blp A 1093-1175 order
       Region 6blp A 1176-1186 disorder
       Region 6blp A 1187-1243 order
       Region 6blp A 1244-1253 disorder
       Region 6blp A 1254-1446 order
       Region 6blp A 1447-1733 disorder
 Evidence X-RAY 6bm2 A Reference
       Region 6bm2 A 1-2 disorder
       Region 6bm2 A 3-148 order
       Region 6bm2 A 149-164 disorder
       Region 6bm2 A 165-185 order
       Region 6bm2 A 186-200 disorder
       Region 6bm2 A 201-250 order
       Region 6bm2 A 251-258 disorder
       Region 6bm2 A 259-1080 order
       Region 6bm2 A 1081-1092 disorder
       Region 6bm2 A 1093-1175 order
       Region 6bm2 A 1176-1186 disorder
       Region 6bm2 A 1187-1243 order
       Region 6bm2 A 1244-1253 disorder
       Region 6bm2 A 1254-1446 order
       Region 6bm2 A 1447-1733 disorder
 Evidence X-RAY 6bm4 A Reference
       Region 6bm4 A 1-2 disorder
       Region 6bm4 A 3-148 order
       Region 6bm4 A 149-164 disorder
       Region 6bm4 A 165-185 order
       Region 6bm4 A 186-200 disorder
       Region 6bm4 A 201-250 order
       Region 6bm4 A 251-258 disorder
       Region 6bm4 A 259-1080 order
       Region 6bm4 A 1081-1092 disorder
       Region 6bm4 A 1093-1175 order
       Region 6bm4 A 1176-1186 disorder
       Region 6bm4 A 1187-1243 order
       Region 6bm4 A 1244-1253 disorder
       Region 6bm4 A 1254-1446 order
       Region 6bm4 A 1447-1733 disorder
 Evidence X-RAY 6bqf A Reference
       Region 6bqf A 1-2 disorder
       Region 6bqf A 3-148 order
       Region 6bqf A 149-164 disorder
       Region 6bqf A 165-185 order
       Region 6bqf A 186-200 disorder
       Region 6bqf A 201-250 order
       Region 6bqf A 251-258 disorder
       Region 6bqf A 259-1080 order
       Region 6bqf A 1081-1092 disorder
       Region 6bqf A 1093-1175 order
       Region 6bqf A 1176-1186 disorder
       Region 6bqf A 1187-1243 order
       Region 6bqf A 1244-1253 disorder
       Region 6bqf A 1254-1446 order
       Region 6bqf A 1447-1733 disorder
 Evidence X-RAY 6upx A Reference
       Region 6upx A 1-2 disorder
       Region 6upx A 3-153 order
       Region 6upx A 154-160 disorder
       Region 6upx A 161-186 order
       Region 6upx A 187-198 disorder
       Region 6upx A 199-249 order
       Region 6upx A 250-256 disorder
       Region 6upx A 257-1081 order
       Region 6upx A 1082-1091 disorder
       Region 6upx A 1092-1176 order
       Region 6upx A 1177-1186 disorder
       Region 6upx A 1187-1243 order
       Region 6upx A 1244-1256 disorder
       Region 6upx A 1257-1446 order
       Region 6upx A 1447-1733 disorder
 Evidence X-RAY 6upy A Reference
       Region 6upy A 1-2 disorder
       Region 6upy A 3-153 order
       Region 6upy A 154-160 disorder
       Region 6upy A 161-186 order
       Region 6upy A 187-198 disorder
       Region 6upy A 199-249 order
       Region 6upy A 250-256 disorder
       Region 6upy A 257-314 order
       Region 6upy A 315-318 disorder
       Region 6upy A 319-1081 order
       Region 6upy A 1082-1091 disorder
       Region 6upy A 1092-1176 order
       Region 6upy A 1177-1186 disorder
       Region 6upy A 1187-1243 order
       Region 6upy A 1244-1253 disorder
       Region 6upy A 1254-1446 order
       Region 6upy A 1447-1733 disorder
 Evidence X-RAY 6upz A Reference
       Region 6upz A 1-2 disorder
       Region 6upz A 3-153 order
       Region 6upz A 154-163 disorder
       Region 6upz A 164-186 order
       Region 6upz A 187-198 disorder
       Region 6upz A 199-249 order
       Region 6upz A 250-256 disorder
       Region 6upz A 257-1081 order
       Region 6upz A 1082-1091 disorder
       Region 6upz A 1092-1176 order
       Region 6upz A 1177-1186 disorder
       Region 6upz A 1187-1243 order
       Region 6upz A 1244-1256 disorder
       Region 6upz A 1257-1446 order
       Region 6upz A 1447-1733 disorder
 Evidence X-RAY 6uq0 A Reference
       Region 6uq0 A 1-2 disorder
       Region 6uq0 A 3-153 order
       Region 6uq0 A 154-160 disorder
       Region 6uq0 A 161-186 order
       Region 6uq0 A 187-198 disorder
       Region 6uq0 A 199-249 order
       Region 6uq0 A 250-256 disorder
       Region 6uq0 A 257-1081 order
       Region 6uq0 A 1082-1091 disorder
       Region 6uq0 A 1092-1176 order
       Region 6uq0 A 1177-1186 disorder
       Region 6uq0 A 1187-1243 order
       Region 6uq0 A 1244-1256 disorder
       Region 6uq0 A 1257-1446 order
       Region 6uq0 A 1447-1733 disorder
 Evidence X-RAY 6uq1 A Reference
       Region 6uq1 A 1-2 disorder
       Region 6uq1 A 3-153 order
       Region 6uq1 A 154-163 disorder
       Region 6uq1 A 164-186 order
       Region 6uq1 A 187-198 disorder
       Region 6uq1 A 199-249 order
       Region 6uq1 A 250-256 disorder
       Region 6uq1 A 257-1081 order
       Region 6uq1 A 1082-1091 disorder
       Region 6uq1 A 1092-1176 order
       Region 6uq1 A 1177-1186 disorder
       Region 6uq1 A 1187-1243 order
       Region 6uq1 A 1244-1256 disorder
       Region 6uq1 A 1257-1446 order
       Region 6uq1 A 1447-1733 disorder
 Evidence X-RAY 6uq2 A Reference
       Region 6uq2 A 1-2 disorder
       Region 6uq2 A 3-153 order
       Region 6uq2 A 154-160 disorder
       Region 6uq2 A 161-186 order
       Region 6uq2 A 187-198 disorder
       Region 6uq2 A 199-249 order
       Region 6uq2 A 250-256 disorder
       Region 6uq2 A 257-1081 order
       Region 6uq2 A 1082-1091 disorder
       Region 6uq2 A 1092-1176 order
       Region 6uq2 A 1177-1187 disorder
       Region 6uq2 A 1188-1243 order
       Region 6uq2 A 1244-1256 disorder
       Region 6uq2 A 1257-1446 order
       Region 6uq2 A 1447-1733 disorder
 Evidence X-RAY 6uq3 A Reference
       Region 6uq3 A 1-2 disorder
       Region 6uq3 A 3-153 order
       Region 6uq3 A 154-160 disorder
       Region 6uq3 A 161-186 order
       Region 6uq3 A 187-198 disorder
       Region 6uq3 A 199-249 order
       Region 6uq3 A 250-256 disorder
       Region 6uq3 A 257-1081 order
       Region 6uq3 A 1082-1091 disorder
       Region 6uq3 A 1092-1176 order
       Region 6uq3 A 1177-1186 disorder
       Region 6uq3 A 1187-1243 order
       Region 6uq3 A 1244-1256 disorder
       Region 6uq3 A 1257-1446 order
       Region 6uq3 A 1447-1733 disorder
 Evidence X-RAY 7ked A Reference
       Region 7ked A 1-2 disorder
       Region 7ked A 3-153 order
       Region 7ked A 154-160 disorder
       Region 7ked A 161-186 order
       Region 7ked A 187-198 disorder
       Region 7ked A 199-249 order
       Region 7ked A 250-256 disorder
       Region 7ked A 257-1081 order
       Region 7ked A 1082-1091 disorder
       Region 7ked A 1092-1176 order
       Region 7ked A 1177-1187 disorder
       Region 7ked A 1188-1243 order
       Region 7ked A 1244-1256 disorder
       Region 7ked A 1257-1446 order
       Region 7ked A 1447-1733 disorder
 Evidence X-RAY 7kee A Reference
       Region 7kee A 1-2 disorder
       Region 7kee A 3-149 order
       Region 7kee A 150-160 disorder
       Region 7kee A 161-186 order
       Region 7kee A 187-198 disorder
       Region 7kee A 199-1081 order
       Region 7kee A 1082-1091 disorder
       Region 7kee A 1092-1176 order
       Region 7kee A 1177-1186 disorder
       Region 7kee A 1187-1243 order
       Region 7kee A 1244-1253 disorder
       Region 7kee A 1254-1445 order
       Region 7kee A 1446-1733 disorder
 Evidence X-RAY 7kef A Reference
       Region 7kef A 1-2 disorder
       Region 7kef A 3-149 order
       Region 7kef A 150-160 disorder
       Region 7kef A 161-186 order
       Region 7kef A 187-198 disorder
       Region 7kef A 199-1081 order
       Region 7kef A 1082-1091 disorder
       Region 7kef A 1092-1176 order
       Region 7kef A 1177-1186 disorder
       Region 7kef A 1187-1243 order
       Region 7kef A 1244-1253 disorder
       Region 7kef A 1254-1445 order
       Region 7kef A 1446-1733 disorder
 Evidence X-RAY 7rim A Reference
       Region 7rim A 1-2 disorder
       Region 7rim A 3-153 order
       Region 7rim A 154-160 disorder
       Region 7rim A 161-186 order
       Region 7rim A 187-198 disorder
       Region 7rim A 199-249 order
       Region 7rim A 250-256 disorder
       Region 7rim A 257-1081 order
       Region 7rim A 1082-1091 disorder
       Region 7rim A 1092-1176 order
       Region 7rim A 1177-1187 disorder
       Region 7rim A 1188-1243 order
       Region 7rim A 1244-1256 disorder
       Region 7rim A 1257-1446 order
       Region 7rim A 1447-1733 disorder
 Evidence X-RAY 7rip A Reference
       Region 7rip A 1-2 disorder
       Region 7rip A 3-153 order
       Region 7rip A 154-160 disorder
       Region 7rip A 161-186 order
       Region 7rip A 187-198 disorder
       Region 7rip A 199-249 order
       Region 7rip A 250-256 disorder
       Region 7rip A 257-1081 order
       Region 7rip A 1082-1091 disorder
       Region 7rip A 1092-1176 order
       Region 7rip A 1177-1187 disorder
       Region 7rip A 1188-1243 order
       Region 7rip A 1244-1256 disorder
       Region 7rip A 1257-1446 order
       Region 7rip A 1447-1733 disorder
 Evidence X-RAY 7riq A Reference
       Region 7riq A 1-2 disorder
       Region 7riq A 3-153 order
       Region 7riq A 154-160 disorder
       Region 7riq A 161-186 order
       Region 7riq A 187-198 disorder
       Region 7riq A 199-249 order
       Region 7riq A 250-256 disorder
       Region 7riq A 257-1081 order
       Region 7riq A 1082-1091 disorder
       Region 7riq A 1092-1176 order
       Region 7riq A 1177-1187 disorder
       Region 7riq A 1188-1446 order
       Region 7riq A 1447-1733 disorder
 Evidence X-RAY 7riw A Reference
       Region 7riw A 1-2 disorder
       Region 7riw A 3-153 order
       Region 7riw A 154-160 disorder
       Region 7riw A 161-186 order
       Region 7riw A 187-198 disorder
       Region 7riw A 199-249 order
       Region 7riw A 250-256 disorder
       Region 7riw A 257-1081 order
       Region 7riw A 1082-1091 disorder
       Region 7riw A 1092-1176 order
       Region 7riw A 1177-1187 disorder
       Region 7riw A 1188-1243 order
       Region 7riw A 1244-1256 disorder
       Region 7riw A 1257-1446 order
       Region 7riw A 1447-1733 disorder
 Evidence X-RAY 7rix A Reference
       Region 7rix A 1-2 disorder
       Region 7rix A 3-153 order
       Region 7rix A 154-160 disorder
       Region 7rix A 161-186 order
       Region 7rix A 187-198 disorder
       Region 7rix A 199-249 order
       Region 7rix A 250-256 disorder
       Region 7rix A 257-1081 order
       Region 7rix A 1082-1091 disorder
       Region 7rix A 1092-1176 order
       Region 7rix A 1177-1187 disorder
       Region 7rix A 1188-1243 order
       Region 7rix A 1244-1256 disorder
       Region 7rix A 1257-1446 order
       Region 7rix A 1447-1733 disorder
 Evidence X-RAY 7riy A Reference
       Region 7riy A 1-2 disorder
       Region 7riy A 3-153 order
       Region 7riy A 154-160 disorder
       Region 7riy A 161-186 order
       Region 7riy A 187-198 disorder
       Region 7riy A 199-249 order
       Region 7riy A 250-256 disorder
       Region 7riy A 257-1081 order
       Region 7riy A 1082-1091 disorder
       Region 7riy A 1092-1176 order
       Region 7riy A 1177-1187 disorder
       Region 7riy A 1188-1243 order
       Region 7riy A 1244-1256 disorder
       Region 7riy A 1257-1446 order
       Region 7riy A 1447-1733 disorder
Seq 1-1733 Hetero dodecamer : P08518,P16370,P20433,P20434,P20435,P20436,P27999,P34087,P38902
 Evidence X-RAY 3qt1 A Reference
       Region 3qt1 A 1-1 disorder
       Region 3qt1 A 2-186 order
       Region 3qt1 A 187-194 disorder
       Region 3qt1 A 195-1081 order
       Region 3qt1 A 1082-1091 disorder
       Region 3qt1 A 1092-1175 order
       Region 3qt1 A 1176-1186 disorder
       Region 3qt1 A 1187-1244 order
       Region 3qt1 A 1245-1253 disorder
       Region 3qt1 A 1254-1455 order
       Region 3qt1 A 1456-1733 disorder
Seq 1-1733 Hetero undecamer : P08518,P16370,P20434,P20435,P20436,P27999,P38902,P85421
 Evidence X-RAY 1k83 A Reference
       Region 1k83 A 1-4 disorder
       Region 1k83 A 5-39 order
       Region 1k83 A 40-48 disorder
       Region 1k83 A 49-187 order
       Region 1k83 A 188-195 disorder
       Region 1k83 A 196-247 order
       Region 1k83 A 248-259 disorder
       Region 1k83 A 260-311 order
       Region 1k83 A 312-323 disorder
       Region 1k83 A 324-336 order
       Region 1k83 A 337-344 disorder
       Region 1k83 A 345-1081 order
       Region 1k83 A 1082-1091 disorder
       Region 1k83 A 1092-1175 order
       Region 1k83 A 1176-1186 disorder
       Region 1k83 A 1187-1243 order
       Region 1k83 A 1244-1253 disorder
       Region 1k83 A 1254-1450 order
       Region 1k83 A 1451-1733 disorder
 Evidence X-RAY 3cqz A Reference
       Region 3cqz A 1-5 disorder
       Region 3cqz A 6-40 order
       Region 3cqz A 41-47 disorder
       Region 3cqz A 48-187 order
       Region 3cqz A 188-195 disorder
       Region 3cqz A 196-248 order
       Region 3cqz A 249-262 disorder
       Region 3cqz A 263-304 order
       Region 3cqz A 305-345 disorder
       Region 3cqz A 346-1178 order
       Region 3cqz A 1179-1186 disorder
       Region 3cqz A 1187-1243 order
       Region 3cqz A 1244-1252 disorder
       Region 3cqz A 1253-1388 order
       Region 3cqz A 1389-1397 disorder
       Region 3cqz A 1398-1450 order
       Region 3cqz A 1451-1733 disorder
Seq 2-1733 Hetero tridecamer : P08518,P16370,P20433,P20434,P20435,P20436,P27999,P34087,P38902
 Evidence X-RAY 5ip7 A Reference
       Region 5ip7 A 2-2 disorder
       Region 5ip7 A 3-186 order
       Region 5ip7 A 187-194 disorder
       Region 5ip7 A 195-1086 order
       Region 5ip7 A 1087-1090 disorder
       Region 5ip7 A 1091-1176 order
       Region 5ip7 A 1177-1186 disorder
       Region 5ip7 A 1187-1244 order
       Region 5ip7 A 1245-1253 disorder
       Region 5ip7 A 1254-1454 order
       Region 5ip7 A 1455-1733 disorder
 Evidence X-RAY 5ip9 A Reference
       Region 5ip9 A 2-2 disorder
       Region 5ip9 A 3-186 order
       Region 5ip9 A 187-194 disorder
       Region 5ip9 A 195-1086 order
       Region 5ip9 A 1087-1090 disorder
       Region 5ip9 A 1091-1176 order
       Region 5ip9 A 1177-1186 disorder
       Region 5ip9 A 1187-1244 order
       Region 5ip9 A 1245-1253 disorder
       Region 5ip9 A 1254-1454 order
       Region 5ip9 A 1455-1733 disorder
Seq 1468-1500 Hetero dimer : IID50042Complex
 Evidence X-RAY 5vko B Reference
       Region 5vko B 1468-1468 disorder
       Region 5vko B 1469-1499 order
       Region 5vko B 1500-1500 disorder
Seq 1476-1498 Hetero dimer : IID50042Complex
 Evidence X-RAY 5vkl B Reference
       Region 5vkl B 1476-1478 disorder
       Region 5vkl B 1479-1498 order
Seq 1619-1653 Hetero octamer : P32569,P38304,P38782
 Evidence X-RAY 4gwq H Reference
       Region 4gwq H 1619-1623 disorder
       Region 4gwq H 1624-1648 order
       Region 4gwq H 1649-1653 disorder
Seq 1672-1690 Hetero pentamer : Q9VWE4
 Evidence X-RAY 6npw E Reference
       Region 6npw E 1672-1676 disorder
       Region 6npw E 1677-1681 order
       Region 6npw E 1682-1690 disorder
Seq 1673-1688 Hetero dimer :
 Evidence NMR 5lvf B Reference
       Region 5lvf B 1673-1688 order
Seq 1675-1688 Hetero dimer : P53617
 Evidence NMR 2lo6 B Reference
       Region 2lo6 B 1675-1688 order
Seq 1675-1688 Hetero dimer : Q05543
 Evidence NMR 2l0i B Reference
       Region 2l0i B 1675-1679 disorder
       Region 2l0i B 1680-1688 order
Seq 1678-1693 Hetero dimer :
 Evidence NMR 5m9d B Reference
       Region 5m9d B 1678-1693 order
SeqProS verified 1469-1499 Hetero dimer : IID50042Complex
       Region 5vko B 1469-1499 order
       Region 1twf A 1451-1733 disorder
SeqProS verified 1479-1498 Hetero dimer : IID50042Complex
       Region 5vkl B 1479-1498 order
       Region 1twf A 1451-1733 disorder
SeqProS verified 1624-1648 Hetero octamer : P32569,P38304,P38782
       Region 4gwq H 1624-1648 order
       Region 1twf A 1451-1733 disorder
SeqProS verified 1673-1688 Hetero dimer :
       Region 5lvf B 1673-1688 order
       Region 1twf A 1451-1733 disorder
SeqProS verified 1675-1688 Hetero dimer : P53617
       Region 2lo6 B 1675-1688 order
       Region 1twf A 1451-1733 disorder
SeqProS verified 1677-1681 Hetero pentamer : Q9VWE4
       Region 6npw E 1677-1681 order
       Region 1twf A 1451-1733 disorder
SeqProS verified 1678-1693 Hetero dimer :
       Region 5m9d B 1678-1693 order
       Region 1twf A 1451-1733 disorder
SeqProS verified 1680-1688 Hetero dimer : Q05543
       Region 2l0i B 1680-1688 order
       Region 1twf A 1451-1733 disorder
Seqphosphorylation
    1471-1471 Phosphothreonine
 
Prediction
NeProc
Disorder 1-2,190-195,255-258,319-337,1457-1733
Order 3-189,196-254,259-318,338-1244,1256-1456
ProS 1-2,319-337,1465-1475,1483-1497,1506-1515,1521-1525,1541-1545,1568-1581,1593-1607,1623-1629,1637-1661,1678-1721
AlphaFold
Disorder 1-5,44-45,187-195,421-422,706-707,1079-1094,1177-1183,1245-1254,1359-1359,1455-1733
Order 6-43,46-186,196-420,423-705,708-1078,1095-1176,1184-1244,1255-1358,1360-1454
Pfam Hmmer
342->507 11-340 510->669
SEG 240-248 ,1538-1719
Function
Function in SwissProt
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. During a transcription cycle, Pol II, general transcription factors and the Mediator complex assemble as the preinitiation complex (PIC) at the promoter. 11-15 base pairs of DNA surrounding the transcription start site are melted and the single-stranded DNA template strand of the promoter is positioned deeply within the central active site cleft of Pol II to form the open complex. After synthesis of about 30 bases of RNA, Pol II releases its contacts with the core promoter and the rest of the transcription machinery (promoter clearance) and enters the stage of transcription elongation in which it moves on the template as the transcript elongates. Pol II appears to oscillate between inactive and active conformations at each step of nucleotide addition. Elongation is influenced by the phosphorylation status of the C-terminal domain (CTD) of Pol II largest subunit (RPB1), which serves as a platform for assembly of factors that regulate transcription initiation, elongation, termination and mRNA processing. Pol II is composed of mobile elements that move relative to each other. The core element with the central large cleft comprises RPB3, RBP10, RPB11, RPB12 and regions of RPB1 and RPB2 forming the active center. The clamp element (portions of RPB1, RPB2 and RPB3) is connected to the core through a set of flexible switches and moves to open and close the cleft. A bridging helix emanates from RPB1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol II by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition. In elongating Pol II, the lid loop (RPB1) appears to act as a wedge to drive apart the DNA and RNA strands at the upstream end of the transcription bubble and guide the RNA strand toward the RNA exit groove located near the base of the largely unstructured CTD domain of RPB1. The rudder loop (RPB1) interacts with single-stranded DNA after separation from the RNA strand, likely preventing reassociation with the exiting RNA. The cleft is surrounded by jaws: an upper jaw formed by portions of RBP1, RPB2 and RPB9, and a lower jaw, formed by RPB5 and portions of RBP1. The jaws are thought to grab the incoming DNA template, mainly by RPB5 direct contacts to DNA.