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IID50443
 UniprotP40458
ProteinAutophagy-related protein 32
GeneATG32
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c)
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
529
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 85-90 Hetero dimer : P38182
 Evidence X-RAY 3vxw B Reference
       Region 3vxw B 85-90 order
Seq 200-341 Monomer :
 Evidence NMR 5wlp A Reference
       Region 5wlp A 200-341 order
       Region 5wlp A 200-214 high_rmsd
       Region 5wlp A 339-341 high_rmsd
SeqProS predicted 85-90 This region is predicted to be disordered by NeProc and AlphaFold (pLDDT < 68.5). Hetero dimer : P38182
       Region 3vxw B 85-90 order
Seqphosphorylation
    119-119 Phosphoserine
    114-114 Phosphoserine
 
Prediction
NeProc
Disorder 1-78,81-94,104-205,342-380,427-450
Order 79-80,95-103,206-341,381-417,455-529
ProS 1-8,37-55,81-94,104-116,130-137,150-195,201-205,342-352,372-380,433-441
AlphaFold
Disorder 1-215,246-246,339-389,414-414,416-479,486-486,489-489,493-518,528-529
Order 216-245,247-338,390-413,415-415,480-485,487-488,490-492,519-527
SEG 10-24 ,120-127 ,174-188 ,307-318 ,340-350 ,362-385 ,428-440
Function
Function in SwissProt
Mitophagy-specific receptor that recruits the autophagic machinery to mitochondria and regulates selective degradation of mitochondria. Mitophagy contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Recruits ATG11 to the surface of mitochondria. Promotes also autophagy-dependent peroxisome degradation.