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IID50456
 UniprotQ63511
ProteinG protein-activated inward rectifier potassium channel 3
GeneKcnj9
OrganismRattus norvegicus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
393
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 388-393 Hetero dimer : Q8K4V4
 Evidence X-RAY 3qgl F Reference
       Region 3qgl F 388-393 order
 Evidence X-RAY 3qgl G Reference
       Region 3qgl G 388-393 order
 Evidence X-RAY 3qgl H Reference
       Region 3qgl H 388-393 order
 Evidence X-RAY 3qgl I Reference
       Region 3qgl I 388-393 order
 Evidence X-RAY 3qgl J Reference
       Region 3qgl J 388-393 order
Seq 388-393 Hetero tetramer : Q8K4V4
 Evidence X-RAY 3qe1 A Reference
       Region 3qe1 A 388-393 order
Seq 388-393 Hetero tetramer : Q8K4V4
 Evidence X-RAY 3qdo A Reference
       Region 3qdo A 388-393 order
SeqProS possible 388-393 PDZ domain-binding motif; this region is predicted to be disordered by AlphaFold (pLDDT <68.5) and NeProc. Hetero dimer : Q8K4V4
       Region 3qgl F 388-393 order
       Region 3qgl G 388-393 order
       Region 3qgl H 388-393 order
       Region 3qgl I 388-393 order
       Region 3qgl J 388-393 order
SeqProS possible 388-393 PDZ domain-binding motif; this region is predicted to be disordered by AlphaFold (pLDDT <68.5) and NeProc. Hetero tetramer : Q8K4V4
       Region 3qe1 A 388-393 order
SeqProS possible 388-393 PDZ domain-binding motif; this region is predicted to be disordered by AlphaFold (pLDDT <68.5) and NeProc. Hetero tetramer : Q8K4V4
       Region 3qdo A 388-393 order
 
Prediction
NeProc
Disorder 1-20,342-393
Order 21-341
ProS 6-11,348-365,378-386
AlphaFold
Disorder 1-20,349-393
Order 21-348
SEG 9-21 ,335-345 ,362-377
Function
Function in SwissProt
This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium (By similarity).