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IID50463
UniprotQ8R3R8
ProteinGamma-aminobutyric acid receptor-associated protein-like 1
GeneGabarapl1
OrganismMus musculus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
117
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-117 Hetero trimer : P22723
 Evidence X-RAY 7cdb A Reference
       Region 7cdb A 1-117 order
 Evidence X-RAY 7cdb B Reference
       Region 7cdb B 1-117 order
Seq 1-117 Hetero dimer : IID50418Complex
 Evidence X-RAY 5yip A Reference
       Region 5yip A 1-117 order
 
Prediction
NeProc
Disorder 114-117
Order 1-85,91-113
ProS 114-117
AlphaFold
Disorder 115-117
Order 1-114
Function
Function in SwissProt
Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover.