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IID50467
 UniprotQ99325
ProteinAutophagy-related protein 40
GeneATG40
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c)
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
256
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 237-252 Hetero dimer : P38182
 Evidence X-RAY 7brn A Reference
       Region 7brn A 237-252 order
 
Prediction
NeProc
Disorder 1-4,29-40,206-234,250-256
Order 5-28,41-205,235-249
ProS 1-4,29-34,206-221,228-234,250-256
AlphaFold
Disorder 1-2,30-50,73-80,82-83,85-85,114-152,155-155,166-171,190-256
Order 3-29,51-72,81-81,84-84,86-113,153-154,156-165,172-189
SEG 35-45 ,222-238
Function
Function in SwissProt
Acts as a receptor for reticulophagy. Directs autophagic sequestration of folded tubules/sheets derived from the cortical endoplasmic reticulum (cER) and the cytoplasmic endoplasmic reticulum (cytoER) into autophagosomes. Is not required for the cytoplasm-to-vacuole targeting pathway, mitophagy, pexophagy, and non-selective autophagy.