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IID00935
 UniprotP31431
ProteinSyndecan-4
GeneSDC4
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
198
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 171-198 Homo dimer :
 Evidence NMR 1ejp A Reference
       Region 1ejp A 171-198 order
       Region 1ejp A 171-178 disorder
       Region 1ejp A 171-178 high_rmsd
       Region 1ejp A 193-198 disorder
       Region 1ejp A 193-198 high_rmsd
 Evidence NMR 1ejp B Reference
       Region 1ejp B 171-198 order
       Region 1ejp B 171-178 disorder
       Region 1ejp B 171-178 high_rmsd
       Region 1ejp B 193-198 disorder
       Region 1ejp B 193-198 high_rmsd
 Evidence NMR 1ejq A Reference
       Region 1ejq A 171-198 order
       Region 1ejq A 171-179 disorder
       Region 1ejq A 171-179 high_rmsd
       Region 1ejq A 195-198 disorder
       Region 1ejq A 195-198 high_rmsd
 Evidence NMR 1ejq B Reference
       Region 1ejq B 171-198 order
       Region 1ejq B 171-179 disorder
       Region 1ejq B 171-179 high_rmsd
       Region 1ejq B 195-198 disorder
       Region 1ejq B 195-198 high_rmsd
Seq 182-198 Hetero tetramer : O00560
 Evidence X-RAY 1ybo C Reference
       Region 1ybo C 182-192 disorder
       Region 1ybo C 193-198 order
 Evidence X-RAY 1ybo D Reference
       Region 1ybo D 182-194 disorder
       Region 1ybo D 195-198 order
 Evidence X-RAY 8blv C Reference
       Region 8blv C 191-198 order
 Evidence X-RAY 8blv D Reference
       Region 8blv D 191-198 order
Seq 193-198 Hetero tetramer : O00560
 Evidence X-RAY 1oby P Reference
       Region 1oby P 193-193 disorder
       Region 1oby P 194-198 order
 Evidence X-RAY 1oby Q Reference
       Region 1oby Q 193-198 order
SeqProS verified 193-198 Hetero tetramer : O00560
       Region 1oby P 194-198 order
       Region 1oby Q 193-198 order
       Region 1ejp A 193-198 disorder
SeqProS verified 193-198 Hetero tetramer : O00560
       Region 1ybo C 193-198 order
       Region 1ybo D 195-198 order
       Region 1ejp A 193-198 disorder
 
Prediction
NeProc
Disorder 1-145,169-198
Order 146-168
ProS 1-68,81-91,97-105,111-125,137-145,169-198
AlphaFold
Disorder 1-4,6-6,14-25,27-27,29-87,91-138,174-190,197-198
Order 5-5,7-13,26-26,28-28,88-90,139-173,191-196
SEG 6-18 ,54-72
Function
Function in SwissProt
Cell surface proteoglycan which regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413).
Biological Process
Diagram with PDB data
SDC4/SDCBPCrystal structure of the complex of PDZ2 of syntenin with a syndecan-4 peptide.